80575-18-4

Upstream product

• 80575-17-3 {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-hydroxy-acetic acid allyl ester 
• 76431-61-3 Carbonic acid (S)-1-[(2S,3R)-2-(2-allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-azetidin-3-yl]-ethyl ester 2,2,2-trichloro-ethyl ester 
• 80575-16-2 C₇H₁₀NO₂S₃^(1-)*K⁽¹⁺⁾ 
• 76431-28-2 Carbonic acid 1-[1-(tert-butyl-dimethyl-silanyl)-2-ethylsulfanyl-4-oxo-azetidin-3-yl]-ethyl ester 2,2,2-trichloro-ethyl ester 
• 76431-29-3 Carbonic acid 1-(2-ethylsulfanyl-4-oxo-azetidin-3-yl)-ethyl ester 2,2,2-trichloro-ethyl ester 
• 76431-27-1 1-(t-butyldimethylsilyl)-3-(1-hydroxyethyl)-4-ethylthioazetidin-2-one 
• 135920-21-7 N-<(allyloxy)carbonyl>cysteamine 
• 603-35-0 triphenylphosphine 
• 80575-17-3 {(2R,3S)-2-(2-Allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-3-[(S)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-hydroxy-acetic acid allyl ester 
• 76431-61-3 Carbonic acid (R)-1-[(2S,3R)-2-(2-allyloxycarbonylamino-ethylsulfanylthiocarbonylsulfanyl)-4-oxo-azetidin-3-yl]-ethyl ester 2,2,2-trichloro-ethyl ester 

Downstream Products

• 72888-55-2 (5R,6S)-3-(2-Amino-ethylsulfanyl)-6-((S)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 
• 72888-55-2 (5R,6R)-3-(2-Amino-ethylsulfanyl)-6-((S)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 
• 72888-55-2 (5R,6S)-3-(2-Amino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 

Relevant academic research and scientific papers

SYNTHESIS OF RACEMIC, 2-(ALKYLTHIO)-6-(1-HYDROXYETHYL) PENEMS; ATTEMPTED PENEM SYNTHESIS VIA COPPER (I) - PROMOTED CYCLISATIONS

Stereocontrolled syntheses of the diastereoisomeric 6-(1-hydroxyethyl)-2-ethylthio and 2-(2-aminoethylthio)-penem-3-carboxylates from a common monocyclic azetidinone precursor are described.Cu (I)-promoted cyclisation of suitable N/C-3 secopenems is shown to yield "isopenems" (7-oxo-2-thia-1-azabicyclohept-3-enes) as the sole bicyclic product.