80598-93-2Relevant academic research and scientific papers
Method for synthesizing 3-aryl thiopropionamide derivative
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Paragraph 0026, (2020/01/08)
The invention relates to a method for synthesizing a 3-aryl thiopropionamide derivative. The method comprises the following step: by taking an aryl allylene derivative as a substrate, an alkali as a promoter and elemental sulfur as a sulfur source, perfor
Mild method for the conversion of amides to thioamides
Charette, Andre B.,Grenon, Michel
, p. 5792 - 5794 (2007/10/03)
Aqueous ammonium sulfide was found to be an ideal substitute for hydrogen sulfide for the thiolysis of activated amides. High yields of the corresponding thioamides were obtained for a broad range of substrates, using two different procedures that are both operationally simple and inexpensive, as well as amenable to large-scale preparation. Preliminary results indicate that aqueous ammonium sulfide may also replace hydrogen sulfide in the synthesis of thionoesters from amides.
GENERATION OF sec-THIOAMIDE DIANIONS AND THEIR REGIOSELECTIVE REACTION WITH ELECTROPHILES.
Tamaru, Y.,Kagotani, M.,Furukawa, Y.,Amino, Y.,Yoshida, Z.
, p. 3413 - 3416 (2007/10/02)
The enolates of sec-thioamides 8, which are generated by three different methods (scheme II and equation 1), are alkylated selectively at the α-carbon to the thiocarbonyl group.The unusual β'-lithiation to provide an intermediate 11 is observed for N-methyl-α,β-dimethylthioacrylamide and N-methylthiocyclohexenecarboxamide.
