80638-53-5

Basic information

• Product Name: (sec-butylamino)(oxo)acetic acid
• Synonyms: (sec-butylamino)(oxo)acetic acid;acetic acid, [(1-methylpropyl)amino]oxo-;Albb-009524;(sec-butylamino)(oxo)acetic acid(SALTDATA: FREE);2-(butan-2-ylamino)-2-oxoacetic acid;2-(butan-2-ylamino)-2-oxo-ethanoic acid;2-keto-2-(sec-butylamino)acetic acid;2-oxo-2-(sec-butylamino)acetic acid
• CAS NO: 80638-53-5
• Molecular Formula: C6H11NO3
• Molecular Weight: 145.16
• Mol File: 80638-53-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.129g/cm³
• Refractive Index: 1.456
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (sec-butylamino)(oxo)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (sec-butylamino)(oxo)acetic acid(80638-53-5)
• EPA Substance Registry System: (sec-butylamino)(oxo)acetic acid(80638-53-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 80638-53-5(Hazardous Substances Data)

Usage

General Description

(sec-butylamino)(oxo)acetic acid is a chemical compound with a wide range of potential uses in scientific and industrial applications. It is characterized by a carboxylic acid functional group, an oxo group, and a secondary butylamino group. This gives it both acidic and basic properties, allowing it to interact with a wide range of other chemicals. The exact properties of (sec-butylamino)(oxo)acetic acid, like its exact acidity, boiling point, and melting point, depend on factors like its purity and the conditions under which it is stored. Nonetheless, this compound's combinations of functional groups make it useful in a variety of situations.

InChI:InChI=1/C6H11NO3/c1-3-4(2)7-5(8)6(9)10/h4H,3H2,1-2H3,(H,7,8)(H,9,10)

Upstream product

• 33966-50-6 SEC-BUTYLAMINE 
• 144-62-7 oxalic acid 
• 343865-68-9 ethyl N-sec-butyloxamate 

Downstream Products

• 1040762-77-3 C₁₉H₁₆BrClF₃N₃O₃ 

Relevant articles and documents

Oxamic acid analogues as LDH-C4-specific competitive inhibitors

We performed kinetic studies to determine whether oxamate analogues are selective inhibitors of LDH-C4, owing to their potential usefulness in fertility control and treatment of some cancers. These substances were shown to be competitive inhibitors of LDH isozymes and are able to discriminate among subtle differences that differentiate the active sites of LDH-A4, LDH-B4 and LDH-C4. N-Ethyl oxamate was the most potent inhibitor showing the highest affinity for LDH-C4. However, N-propyl oxamate was the most selective inhibitor showing a high degree of selectivity towards LDH-C4. Non-polar four carbon atoms chains, linear or branched, dramatically diminished the affinity and selectivity towards LDH-C4. N-Propyl oxamate significantly reduced ATP levels, capacitation and mouse sperm motility, in line with results shown by others, suggesting that LDH-C4 plays an essential role in mouse fertility.