80645-36-9

Upstream product

• 586-95-8 pyridine-4-methanol 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 80633-28-9 4-picolyl 4'-hydroxy-3'-nitrophenylacetate 

Downstream Products

• 33477-30-4 4-nitrobenzyl ester of N-t-butyloxycarbonyl-L-phenylalanyl-L-leucine 

Relevant academic research and scientific papers

Protected Amino Acid Active Esters Incorporating the 4-Picolyl Basic Solubilizing Group

The 4-picolyl ester of 4-hydroxy-3-nitrophenylacetic acid has been prepared from an active polyester intermediate, and used as the precursor of a series of protected amino acid active esters.These compounds were satifactory coupling components in peptide syntheses.Purification of the protected peptides by acid washing was facilitated by the presence of the basic 4-picolyl moiety.