80645-52-9

Upstream product

• 7504-73-6 2-methylphenyl 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 95-48-7 ortho-cresol 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 19234-04-9 2-(p-methoxyphenyl)-benzo[b]furan 
• 14716-23-5 2-(2-hydroxyphenyl)-4-methoxyacetophenone 
• 97585-35-8 C₃₀H₂₆O₆ 
• 80645-56-3 bromure de p-methoxybenzoyloxy-2 benzyltriphenylphosphonium 

Relevant academic research and scientific papers

Unexpected migration of a benzoyl group in the intramolecular Wittig reaction of o-acyloxybenzylidenephosphoranes with benzoyl chlorides: One-pot synthesis of isomeric 3-benzoyl-2-phenylbenzofurans

The reaction of o-acyloxybenzylidenetriphenylphosphoranes with substituted benzoyl chlorides in an aprotic solvent led, together with the expected 2-phenylbenzofuran, to isomeric 3-benzoyl-2-phenylbenzofuran derivatives. This result formally corresponds to intramolecular migration of the benzoyl group from the ortho oxygen atom to the ylide carbanion via cyclization and ring opening of the starting o-acyloxybenzylidenetriphenylphosphoranes.

A novel photochemical Wittig reaction for the synthesis of 2-aryl/alkylbenzofurans

The synthesis of 2-aryl/alkylbenzofurans has been achieved in high yields under photochemical conditions from readily accessible and suitably substituted phosphonium bromides by an intramolecular photochemical Wittig reaction onto aryloxycarbonyl groups.