80651-65-6

Usage

Chemical structure

A synthetic chemical compound derived from testosterone.

Potency

Potent androgen receptor agonist.

Function

Binds to and activates androgen receptors in the body.

Effects

Increases development and maintenance of male characteristics, and anabolic effects such as increased muscle mass and strength.

Potential applications

Hormone replacement therapy and treatment of conditions related to androgen deficiency.

Limitations

Limited and regulated use due to potential for abuse in sports and bodybuilding.

Legal status

Its use is regulated and may be subject to legal restrictions depending on the jurisdiction.

Safety

The safety and side effects of long-term use are not fully understood and may vary depending on individual factors.

Dosage

Dosage and administration should be determined by a qualified healthcare professional.

Interactions

May interact with other medications or substances, and should be used under the guidance of a healthcare professional.

Upstream product

• 4033-95-8 2-hydroxymethylene-17β-hydroxy-5α-androstan-3-one 
• 521-18-6 Stanolone 
• 4033-95-8 2-hydroxymethylene-17β-hydroxy-5α-androstan-3-one 

Downstream Products

• 18063-40-6 3-cyclohexyl-propionic acid (5α)-androstano[2,3-d]isoxazol-17β-yl ester 
• 107928-83-6 (4-chloro-phenoxy)-acetic acid (5α)-androstano[2,3-d]isoxazol-17β-yl ester 

Relevant academic research and scientific papers

A simple method for the small scale synthesis and solid-phase extraction purification of steroid sulfates

Steroid sulfates are a major class of steroid metabolite that are of growing importance in fields such as anti-doping analysis, the detection of residues in agricultural produce or medicine. Despite this, many steroid sulfate reference materials may have limited or no availability hampering the development of analytical methods. We report simple protocols for the rapid synthesis and purification of steroid sulfates that are suitable for adoption by analytical laboratories. Central to this approach is the use of solid-phase extraction (SPE) for purification, a technique routinely used for sample preparation in analytical laboratories around the world. The sulfate conjugates of sixteen steroid compounds encompassing a wide range of steroid substitution patterns and configurations are prepared, including the previously unreported sulfate conjugates of the designer steroids furazadrol (17β-hydroxyandrostan[2,3-d]isoxazole), isofurazadrol (17β-hydroxyandrostan[3,2-c]isoxazole) and trenazone (17β-hydroxyestra-4,9-dien-3-one). Structural characterization data, together with NMR and mass spectra are reported for all steroid sulfates, often for the first time. The scope of this approach for small scale synthesis is highlighted by the sulfation of 1 μg of testosterone (17β-hydroxyandrost-4-en-3-one) as monitored by liquid chromatography-mass spectrometry (LCMS).

Identification of steroid isoxazole isomers marketed as designer supplement

The product Orastan-A from Gaspari Nutrition was analyzed for its steroid content. According to the labeling, it is supposed to contain "5a-Androstano[2,3-c]furazan-17b-tetrahydropyranol ether", also called furazadrol-THP ether. The GC-MS analyses of the