4033-95-8

Basic information

• Product Name: (2E)-17-hydroxy-2-(hydroxymethylidene)androstan-3-one
• CAS NO: 4033-95-8
• Molecular Formula: C₂₀H₃₀O₃
• Molecular Weight: 318.4504
• Mol File: 4033-95-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 464.7°C at 760 mmHg
• Flash Point: 249°C
• Density: 1.197g/cm³
• Vapor Pressure: 1.37E-10mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: (2E)-17-hydroxy-2-(hydroxymethylidene)androstan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-17-hydroxy-2-(hydroxymethylidene)androstan-3-one(4033-95-8)
• EPA Substance Registry System: (2E)-17-hydroxy-2-(hydroxymethylidene)androstan-3-one(4033-95-8)

Safety Data

• Hazardous Substances Data: 4033-95-8(Hazardous Substances Data)

Usage

General Description

(2E)-17-hydroxy-2-(hydroxymethylidene)androstan-3-one, also known as 17-OH-DHEA, is a steroid hormone that is produced in the adrenal glands and is a precursor to the sex hormones estrogen and testosterone. It is an important marker for adrenal function and has been studied for its potential role in aging, immunity, and hormone-related conditions such as polycystic ovary syndrome and adrenal insufficiency. 17-OH-DHEA has also been investigated for its potential as a dietary supplement for improving physical and cognitive function in older adults, as well as its effects on metabolism and body composition. However, more research is needed to fully understand its effects and potential therapeutic applications.

Upstream product

• 521-18-6 Stanolone 
• 109-94-4 formic acid ethyl ester 
• 107-31-3 Methyl formate 
• 571-22-2 5β-androstan-17β-ol-3-one 
• 1164-91-6 stanolone acetate 
• 979-24-8 2-Formil-3-cloro-Δ²-5α-androsten-17β-olo acetato 

Downstream Products

• 86699-40-3 2-(N-methylanilinomethylene)-5α-androstan-17β-ol-3-one 
• 100152-29-2 17β-hydroxy-5α-androstan[3,2-c]isoxazole 
• 80651-65-6 17β-hydroxy-5α-androst-2-eno<2,3-d>isoxazole 
• 58-19-5 dromostanolone 
• 5470-27-9 2α-Methyl-5α-androstan-3,17-dion 

Relevant articles and documents

NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

Described herein are neuroactive steroids of the Formula (I): (Formula (I)) or a pharmaceutically acceptable salt thereof; wherein R1a and R1b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

Identification of steroid isoxazole isomers marketed as designer supplement

The product Orastan-A from Gaspari Nutrition was analyzed for its steroid content. According to the labeling, it is supposed to contain "5a-Androstano[2,3-c]furazan-17b-tetrahydropyranol ether", also called furazadrol-THP ether. The GC-MS analyses of the