80675-86-1

Upstream product

• 54-96-6 3,4-diaminopyridine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 619-84-1 p-N,N-dimethylaminobenzoic acid 
• 1681-37-4 4-amino-3-nitropyridine 

Relevant academic research and scientific papers

Spectral characteristics of 2-(4′-N,N-dimethylaminophenyl)pyrido[3,4-d]imidazole in AOT/n-heptane/water reverse micelles

Spectral characteristics of 2-(4′-N,N-dimethylaminophenyl)pyrido[3,4-d]imidazole (DMAPPI) have been studied in AOT/n-heptane/water reverse micelles at w0≥0. Absorption, fluorescence excitation and fluorescence spectra have revealed that the mon

Relay proton transfer triggered twisted intramolecular charge transfer

The mechanism for the dual emission of 2-(4′-N,N-dimethylaminophenyl)imidazo[4,5-c]pyridine (DMAPIP-c) in protic solvents was investigated by synthesizing and studying its analogues. Theoretical calculations were carried out to corroborate the experimental findings. The deprotonation studies suggest that the enhancement in the TICT emission of anionic forms of DMAPIP-c is limited to a protic environment. The spectral characteristics of DMAPIP-c were also studied in a methanol-acetonitrile binary solvent mixture. Unlike DMAPIP-c, the methyl derivatives do not emit dual fluorescence in protic solvents. The relative intensity of the TICT emission (with respect to that of normal emission) rises with the methanol amount in the acetonitrile-methanol binary solvent mixture. The studies also show that a 1:3 hydrogen bonded complex is formed between DMAPIP-c and methanol and it is responsible for the TICT emission. Based on the results a relay proton transfer tiggered TICT emission is proposed. TDDFT calculations were performed to predict the emission energies.

Na2S2O4: A versatile reagent for the one-pot synthesis of 2-aryl-1h-imidazo[4,5-c]pyridines from 4-amino-3- nitropyridine and aldehydes via reductive cyclization

A highly efficient and versatile method for the synthesis of 2-aryl-1H-imidazo[4,5-c]pyridines 3 was achieved in one step via reductive cyclization of 4-amino-3-nitro-pyridines 4 with aromatic aldehydes in the presence of Na2S2O

Hit generation and exploration: Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases

A hit generation and exploration approach led to the discovery of 31 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide), a potent, novel inhibitor of Aurora-A, Aurora-B and Aurora-C kinases

2-phenylimidazio (4,5-c) pyridines

This invention provides for certain 2-phenylimidazo[4,5-c]pyridines, their pharmaceutical formulations, and their use as positive inotropic agents, bronchodilators, vasodilators, and anticoagulants.

PREPARATION OF 2-ARYL-SUBSTITUTED IMIDAZOPYRIDINES AND IMIDAZOPYRIDINES

It is proposed that sulfur be used as the oxidizing agent in the synthesis of 2-arylimidazopyridines from o-diaminopyridines and aromatic (heteroaromatic) aldehydes.Benzyl alcohols and benzylpyridinium salts can be used in place of aldehydes. 2-Phenylimid