55234-56-5

Basic information

• Product Name: 4-(4-METHOXYPHENYL)-4-OXOBUTANENITRILE
• Synonyms: 4-(4-METHOXYPHENYL)-4-OXOBUTANENITRILE;4-(4-METHOXYPHENYL)-4-OXOBUTYRONITRILE
• CAS NO: 55234-56-5
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21
• Mol File: 55234-56-5.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 385°C at 760 mmHg
• Flash Point: 168.4°C
• Appearance: /
• Density: 1.104g/cm³
• Vapor Pressure: 3.93E-06mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: 4-(4-METHOXYPHENYL)-4-OXOBUTANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-METHOXYPHENYL)-4-OXOBUTANENITRILE(55234-56-5)
• EPA Substance Registry System: 4-(4-METHOXYPHENYL)-4-OXOBUTANENITRILE(55234-56-5)

Safety Data

• Hazardous Substances Data: 55234-56-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H11NO2/c1-14-10-6-4-9(5-7-10)11(13)3-2-8-12/h4-7H,2-3H2,1H3

Upstream product

• 71818-80-9 2-(4-methoxy-phenyl)-2-morpholin-4-yl-pentanedinitrile 
• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 
• 1456628-06-0 2-(2-chloroethyl)-2-(4-methoxyphenyl)-1,3-dithiane 
• 100-07-2 4-methoxy-benzoyl chloride 
• 107-13-1 acrylonitrile 
• 63261-18-7 1-(4-Methoxy-phenyl)-3-[3-(4-methoxy-phenyl)-3-oxo-propane-1-sulfonyl]-propan-1-one 
• 143-33-9 sodium cyanide 
• 107-14-2 chloroacetonitrile 
• 80676-78-4 tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane 
• 110-61-2 butanedinitrile 
• 5720-07-0 4-methoxyphenylboronic acid 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 22390-98-3 1-(4-methoxyphenyl)ethenyl acetate 
• 75-05-8 acetonitrile 

Downstream Products

• 77147-94-5 3-(4-Methoxy-benzoyl)-4,4-bis-methylsulfanyl-but-3-enenitrile 
• 1456628-15-1 (S)-4-hydroxy-4-(4-methoxyphenyl)butanenitrile 
• 26153-41-3 γ-(4-methoxyphenyl)-γ-butyrolactone 
• 7182-43-6 4-(4-hydroxy-phenyl)-4-oxo-butyronitrile 
• 3153-44-4 4-(4-methoxy-phenyl)-4-oxo-butyric acid 
• 74190-66-2 2-(4-methoxyphenyl)pyrrolidine 
• 22217-80-7 2-(4-methoxyphenyl)-1-pyrroline 

Relevant articles and documents

Facile Synthesis of γ-Ketonitriles in Water via C(sp2)–H Activation of Aromatic Aldehydes over Cu?g-C3N4 under Visible-Light

A facile C(sp2)–H activation of aldehyde under visible-light conditions using Cu?g-C3N4 as photocatalyst and water as solvent is reported. The envisaged method involves photocatalytic intermolecular Stetter reaction using

A Photochemical Organocatalytic Strategy for the α-Alkylation of Ketones by using Radicals

Reported herein is a visible-light-mediated radical approach to the α-alkylation of ketones. This method exploits the ability of a nucleophilic organocatalyst to generate radicals upon SN2-based activation of alkyl halides and blue light irradiation. The resulting open-shell intermediates are then intercepted by weakly nucleophilic silyl enol ethers, which would be unable to directly attack the alkyl halides through a traditional two-electron path. The mild reaction conditions allowed functionalization of the α position of ketones with functional groups that are not compatible with classical anionic strategies. In addition, the redox-neutral nature of this process makes it compatible with a cinchona-based primary amine catalyst, which was used to develop a rare example of enantioselective organocatalytic radical α-alkylation of ketones.

A Novel Ketonitrile Synthesis by Palladium-Catalyzed Carbonylative Coupling Reactions of Amides with Arylboronic Acids

A novel, efficient, and simple procedure to synthesize diverse ketonitriles by palladium-catalyzed Suzuki coupling of amides through N–C cleavage has been developed. This procedure features mild conditions, a broad substrate scope, and easily prepared substrates, providing a simple and efficient access to a variety of ketonitriles.