80703-89-5

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 1310-58-3 potassium hydroxide 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 917-64-6 methyl magnesium iodide 
• 14305-27-2 3-(4-chlorophenyl)-2,2-dimethylpropanoic acid methyl ester 

Downstream Products

• 89441-41-8 1-(4-chlorophenyl)-1-bromo-2,2-dimethyl-3-butanone 
• 80691-92-5 5-amino-1-(4-chlorophenyl)-2,2-dimethyl-3-hexanone 
• 80692-04-2 6-(4-chlorophenyl)-5,5-dimethyl-2,4-hexandione 

Relevant academic research and scientific papers

NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES

The present invention relates to novel heterocyclic alkanol derivatives, to processes for these compounds, to compositions comprising these compounds and to their use as biologically active compounds, in particular for controlling harmful microorganisms i

Preparation of 2,2-dimethyl-3-aryl-cyclopropanecarboxylic acid and esters and new intermediates therefor

2,2-Dimethyl-3-arylcyclopropanecarboxylic acids and esters, suitable as insecticide intermediates, of the formula STR1 in which Ar is naphthyl or substituted furyl, thienyl or phenyl, and R1 is hydrogen or alkyl, are produced by subjecting STR2

Preparation of methyl ketones

A process for the preparation of a methyl ketone of the formula STR1 in which R1 is alkyl, alkenyl, alkinyl, optionally substituted aryl or optionally substituted heteroaryl, R2 is alkyl, R3 is alkyl or R2 and R3, together with the carbon atom to which they are bonded, from a cycloalkyl ring, comprising reacting a methyl sec.-alkyl ketone of the formula STR2 with a halide of the formula in which X is halogen, in the presence of a base, a diluent, and a phase-transfer catalyst.

Intermediates in the preparation of 2,2-dimethyl-3-aryl-cyclopropanecarboxylic acids and esters

A process for the preparation of 2,2-dimethyl-3-arylcyclopropanecarboxylic acid or ester of the formula STR1 in which Ar is naphthyl or the radical STR2 R1 is H or C1 -C4 -alkyl, Z is oxygen, sulphur, or 1,2-ethenediyl, an

Inhibitors of neuronal monoamine uptake. III. Synthesis and pharmacologic screening of alaproclate analogues

A series of alaprocate analogues were prepared and evaluated as inhibitors of the neuronal reuptake of noradrenaline and 5-hydroxytryptamine. In the new compounds various molecular moieties were substituted for the ester linkage of alaproclate, a specific