80709-80-4

Usage

Uses

2-Methyl-4h-furo[3,2-b]pyrrole-5-carboxylic acid is a useful intermediate.

Upstream product

• 80709-78-0 2-Methyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester 
• 620-02-0 5-Methylfurfural 
• 80709-72-4 Ethyl 2-azido-3-(5-methyl-2-furyl)acrylate 
• 155445-28-6 methyl 2-methyl-4H-furo[3,2-b]pyrrole-5-carboxylate 

Downstream Products

• 132120-23-1 2-methyl-4-acetylfuro<3,2-b>pyrrole 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of furo[3,2-b]pyrrole derivatives

8-Ethoxyfuro[2′,3′:4,5]pyrrolo[1,2-d][1,2,4]triazine was synthesized by reaction of appropriate triazinone with POCl3 and subsequent treating of 8-chloro derivative with sodium ethoxide in ethanol. Furo[3,2-b]pyrrole-5- carboxylates were hydrolysed to for

FLUORESCENT COMPOUND AND LABELING AGENT COMPRISING THE SAME

A novel fluorescent compound having a high light fastness, high fluorescence quantum yield and sharp absorption spectrum, which emits fluorescence having a wavelength in long wavelength region, as well as its use as a labeling agent, is disclosed. In Form

Bright, color-tunable fluorescent dyes in the Vis/NIR region: Establishment of new "tailor-made" multicolor fluorophores based on borondipyrromethene

A new series of high-performance fluorophores named Keio Fluors (KFL), which are based on borondipyrromethene (BODIPY), are reported. The KFL dyes cover a wide spectral range from the yellow (547 nm) to the near-infrared (NIR, 738 nm) region, and their emission wavelength could be easily and subtly controlled based on simple molecular modifications only, without losing their optical properties. This "tailor-made" synthetic strategy for tuning the emission wavelength enabled the creation of fourteen KFL dyes with well-controlled emission colors (yellow, orange, red, far-red, and NIR). Moreover, these KFL dyes also retain their excellent optical properties, such as spectral bands sharper than quantum dots, high extinction coefficients (140000-316000 M-1 cm-1), and high quantum yields (0.56-0.98), without any critical solvent polarity dependent decrease of their brightness. These advantageous characteristics make the KFL dyes potentially useful as new candidates of fluorescent standard dyes to substitute or to complement existing long-wavelength fluorescent dyes, such as cyanines, oxazines, rhodamines, or other BODIPY dyes.

Bright, color-tunable fluorescent dyes in the visible-near-infrared region

The newly synthesized Keio Fluors, which are based on boron-dipyrromethene (BDP), have excellent and useful optical properties: vivid colors and sharp emission in the visible-near-infrared region (583-738 nm), high quantum yields (Φ: 0.56-0.98), high exti

FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE

This invention provides novel inhibitors of the enzyme D-amino acid oxidase as well as pharmaceutical compositions including the compounds of the invention. The invention also provides methods for the treatment and prevention of neurological disorders, such as neuropsychiatric and neurodegenerative diseases, as well as pain, ataxia and convulsion. The compounds of the invention have the general structure: wherein A is NH or S. Q is a member selected from CR1 and N. X and Y are members independently selected from O, S, CR2, N and NH. R1, R2 and R4 are members independently selected from H and F, provided that at least one member selected from R1, R2 and R4 is F. R6 is a member selected from O?X+ and OH, wherein X+ is a positive ion, which is a member selected from inorganic positive ions and organic positive ions.

Condensed O-, N-Heterocycles by the Transformation of Azidoacrylates

A number of furopyridines (4a-4d) and benzoderivative (4e), as well as pyrrolofuropyridine (8) were prepared by reaction of the corresponding iminophosphoranes, available from ethyl azidoheteroacrylates and triphenylphosphinee,

SYNTHESIS AND REACTIONS OF SUBSTITUTED FUROPYRROLE DERIVATIVES

Preparation of ethyl 2-methylfuropyrrole-5-carboxylate and 2-bromofuropyrrole-5-carboxylate, as well as alkylation and hydrolysis of ethyl 2-methylfuropyrrole-5-carboxylate, ethyl furopyrrole-5-carboxylate and ethyl (3,4-dichlo