80710-70-9Relevant academic research and scientific papers
A mild dihydrobenzooxaphosphole oxazoline/iridium catalytic system for asymmetric hydrogenation of unfunctionalized dialins
Qu, Bo,Samankumara, Lalith P.,Ma, Shengli,Frick, Keith R.,Desrosiers, Jean-Nicolas,Rodriguez, Sonia,Li, Zhibin,Haddad, Nizar,Han, Zhengxu S.,McKellop, Keith,Pennino, Scott,Grinberg, Nelu,Gonnella, Nina C.,Song, Jinhua J.,Senanayake, Chris H.
supporting information, p. 14428 - 14432 (2015/02/19)
Air-stable P-chiral dihydrobenzooxaphosphole oxazoline ligands were designed and synthesized. When they were used in the iridium-catalyzed asymmetric hydrogenation of unfunctionalized 1-aryl-3,4-dihydronaphthalenes under one atmosphere pressure of H2, up to 99:1 e.r. was obtained. High enantioselectivities were also observed in the reduction of the exocyclic imine derivatives of 1-tetralones.
