80715-31-7Relevant academic research and scientific papers
Novel ampicillin esters and production thereof
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, (2008/06/13)
A novel Ampicillin ester of the general formula STR1 wherein R1 represents a hydrogen atom, a methyl group or an aryl group, and R2 represents a hydrogen atom or may be taken together with R1 to form a divalent carbon chai
Ester of 6-[(hexahydro-1H-azepin-1-yl)methyleneamino]penicillanic acid, and its use as antibacterial agent
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, (2008/06/13)
(5-Methyl-2-oxo-1,3-dioxolen-4-yl)methyl 6-[(hexahydro-1H-azepin-1-yl)methyleneamino]penicillanate of the following formula (I) STR1 or its pharmaceutically acceptable acid addition salt. The compound is useful as an antibacterial agent and may be prepared by reacting (5-methyl-2-oxo-1,3-dioxolen-4-yl)-methyl 6-aminopenicillanate of the following formula (II) STR2 or its acid addition salt with chloro-N,N-hexamethyleneformiminium chloride, and as required, converting the resulting compound to its pharmaceutically acceptable acid addition salt.
