807315-42-0

Upstream product

• 24228-41-9 1-(phenylethyl)-4-(ethoxycarbonyl)piperidine 
• 100-42-5 styrene 
• 498-94-2 isonipecotic acid 
• 103-63-9 1-phenyl-2-bromoethane 

Downstream Products

• 1463609-42-8 1H-1-oxa-2-aza-6-chloro-3-(1-phenethylpiperidin-4-yl)-1,4dihydroindeno[2,1-d]isoxazole 
• 1463609-43-9 2H-1-aza-2-oxa-6-chloro-3-(1-phenethylpiperidin-4-yl)-1,4dihydroindeno[1,2-c]isoxazole 
• 1463609-41-7 phenyl 1-phenethylpiperidine-4-carboxylate 
• 383362-71-8 4-[(Bis(4-fluorophenyl)methylamino)methyl]-1-[2-(phenyl)ethyl]piperidine 

Relevant academic research and scientific papers

Synthetic method of anesthetic analgesic drug

The invention discloses a synthetic method of an anesthetic analgesic drug. According to the synthetic method, 4-piperidinecarboxylic acid is used as a raw material and subjected to alkylation, bromination, methylation, acylation and the like to prepare the anesthetic analgesic drug. The method avoids the usage of highly toxic cyanide, so the safety and controllability of operation are improved; the method avoids an elimination reaction in reaction process, thereby accelerating reaction speed and shortening reaction time; and the method reduces reaction temperature, shortens the reaction time,and is more suitable for industrial production.

N-and o-substituted 4-[2-( diphenylmethoxy) -ethyl]-1- (phenyl) methyl) piperidine analogs and methods of treating cns disorders therewith

N- and O-substituted 4[2-diaromaticmethoxy and methylamino)alkyl]piperidines exhibit high CNS activity with respect to the dopamine transporter (DAT) and serotonin transporter (SERT). Preferred compounds exhibit highly differential behavior as between the

Structure - Activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: Evaluation of behavioral activity of O- and N-analogues and their binding to monoamine transporters

In our effort to develop a pharmacotherapy for the treatment of cocaine addiction, we embarked on synthesizing novel molecules targeting the dopamine transporter (DAT) molecule in the brain as DAT has been implicated strongly in the reinforcing effect of