807325-83-3

Upstream product

• 773865-48-8 6-iodo-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 951006-38-5 diethyl 2-(((4-iodo-2-methylphenyl)amino)methylene)malonate 
• 951006-39-6 ethyl 6-iodo-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 13194-68-8 4-iodo-2-methylaniline 
• 801315-31-1 4-chloro-6-iodo-8-methylquinoline-3-carboxamide 
• 536-90-3 m-Anisidine 

Downstream Products

• 1346654-83-8 6-((11-hydroxyundecyl)thio)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide 
• 801311-24-0 methyl 3-[[3-carbamoyl-4-[(3-methoxyphenyl)amino]-8-methylquinolin-6-yl]sulfonyl]benzoate 
• 801311-41-1 3-[[3-carbamoyl-4-[(3-methoxyphenyl)amino]-8-methylquinolin-6-yl]sulfonyl]benzoic acid 

Relevant academic research and scientific papers

Repurposing human PDE4 inhibitors for neglected tropical diseases. evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of pdeb1 of trypanosoma brucei

Cyclic nucleotide phosphodiesterases (PDEs) have been identified as important enzyme targets for drug development in both humans and Trypanosoma brucei, the causative agent of human African trypanosomiasis. With this in mind, we recently reported the prof