807331-97-1

Upstream product

• 145679-15-8 methyl α-(p-methylphenyl)propionate 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 220041-95-2 (R)-4-benzyl-3-(2-p-tolylethanoyl)oxazolidin-2-one 
• 122091-54-7 (R)-(+)-2-(4-methylphenyl)propanol 
• 622-47-9 4-tolylacetic acid 
• 937207-94-8 4-benzyl-3-(2-p-tolyl-propionyl)-oxazolidin-2-one 
• 122091-53-6 2-(4-methylphenyl)propanal 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 4179-26-4 (+)-(S)-4-p-Tolyl-pentansaeure-ethylester 
• 25532-74-5 (+)-(S)-nuciferal 
• 3649-81-8 (S)-curcumene 
• 3241-74-5 (S)-4-p-tolylpentanal 
• 937207-96-0 1-(4-benzyl-2-thioxo-oxazolidin-3-yl)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-6-p-tolyl-heptan-1-one 
• 937207-97-1 toluene-4-sulfonic acid 3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-6-p-tolyl-heptyl ester 
• 937207-95-9 1-(4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-2-methyl-6-p-tolyl-heptan-1-one 
• 937208-01-0 3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-6-p-tolyl-heptan-1-ol 
• 937207-98-2 3-methyl-2-(3-p-tolyl-butyl)-oxetane 
• 19876-64-3 (S)-(+)-4-p-tolylpentan-1-ol 

Relevant academic research and scientific papers

An aldol approach to the synthesis of the anti-tubercular agent erogorgiaene

A total synthesis of erogorgiaene is described in 16 steps. The synthesis relies upon a highly diastereoselective intramolecular Friedel-Crafts reaction of an oxetane derived via an asymmetric syn aldol coupling.

Enantioselective synthesis of (+)-nuciferal, (+)-(E)-nuciferol and (+)-α-curcumene by chiral hydrogenesterification reaction

Using chiral hydrogenesterification reaction as the key step, the stereoselective synthesis of (+)-nuciferal 1, (+)-(E)-nuciferol 2 and (+)-a-curcumene 3 has been achieved.