807365-96-4Relevant academic research and scientific papers
The evolution of a stereoselective synthesis of the C1-C16 fragment of bryostatins
Ball, Matthew,Baron, Anne,Bradshaw, Ben,Dumeunier, Rapha?l,O'Brien, Matthew,Thomas, Eric J.
, p. 9650 - 9681 (2016/10/22)
The development of a synthesis of the C1-C16 fragment of bryostatins in which the key step is a stereoselective oxy-Michael reaction used to assemble the cis-2,6-disubstituted tetrahydropyran with the exocyclic alkene already installed, is described. Foll
A stereoselective synthesis of the C(1)-C(16) fragment of the bryostatins
Ball, Matthew,Baron, Anne,Bradshaw, Benjamin,Omori, Hiroki,MacCormick, Somhairle,Thomas, Eric J.
, p. 8737 - 8740 (2007/10/03)
A synthesis of the C(1)-C(16) fragment of the brysostatins has been developed. Key steps are the stereoselective copper(I) catalysed addition of allylmagnesium bromide to an alkynyl ester, a condensation of a βγ-unsaturated aldehyde with a ketophosphonate
