807373-27-9

Basic information

• Product Name: Carbamic acid, [(1S,5Z)-1-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-7 -oxo-7-phenyl-5-heptenyl]methyl-, 2,2,2-trichloroethyl ester
• CAS NO: 807373-27-9
• Molecular Formula: C31H42Cl3NO4Si
• Molecular Weight: 627.123
• Mol File: 807373-27-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S,5Z)-1-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-7 -oxo-7-phenyl-5-heptenyl]methyl-, 2,2,2-trichloroethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S,5Z)-1-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-7 -oxo-7-phenyl-5-heptenyl]methyl-, 2,2,2-trichloroethyl ester(807373-27-9)
• EPA Substance Registry System: Carbamic acid, [(1S,5Z)-1-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-7 -oxo-7-phenyl-5-heptenyl]methyl-, 2,2,2-trichloroethyl ester(807373-27-9)

Safety Data

• Hazardous Substances Data: 807373-27-9(Hazardous Substances Data)

Upstream product

• 1070913-26-6 (cis:trans)-(-)-lobeline 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 17341-93-4 2,2,2-Trichloroethyl chloroformate 

Downstream Products

• 497-88-1 (-)-sedamine 
• 807373-38-2 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-5-hydroxypentyl}(methyl)carbamate 
• 807373-52-0 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-5-bromopentyl}(methyl)carbamate 
• 807373-66-6 (2S)-2-((2S)-2-{[tert-butyl(dimethyl)silyl]oxy}-2-phenylethyl)-1-methylpiperidine 

Relevant articles and documents

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids

Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in diverse contexts and the ability of this methodology to set the absolute configuration of multiple stereocenters in a single operation. The utility of an aryne C-C insertion reaction in accessing complex polycyclic frameworks is also described.