80745-10-4

Basic information

• Product Name: H-ARG(MTR)-OH
• Synonyms: NOMEGA-(4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL)-L-ARGININE;NG-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL-L-ARGININE;AMINO ACID SERIES;ARGININE(MTR)-OH;L-ARGINYL-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL;H-ARG(MTR)-OH;H-ARG(MTR)-OH H2O;H-Arg(Mtr)-OH.1/2H2O
• CAS NO: 80745-10-4
• Molecular Formula: C₁₆H₂₆N₄O₅S
• Molecular Weight: 386.47
• Product Categories: chiral;Amino Acids;Amino Acids and Derivatives;Amino Acid Derivatives
• Mol File: 80745-10-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 615.4oC at 760 mmHg
• Flash Point: 326oC
• Appearance: White/Powder
• Density: 1.36g/cm3
• Vapor Pressure: 5.33E-16mmHg at 25°C
• Refractive Index: 1.593
• Storage Temp.: Store at RT.
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: H-ARG(MTR)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-ARG(MTR)-OH(80745-10-4)
• EPA Substance Registry System: H-ARG(MTR)-OH(80745-10-4)

Safety Data

• Hazardous Substances Data: 80745-10-4(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C16H26N4O5S/c1-9-8-13(25-4)10(2)11(3)14(9)26(23,24)20-16(18)19-7-5-6-12(17)15(21)22/h8,12H,5-7,17H2,1-4H3,(H,21,22)(H3,18,19,20)/t12-/m0/s1

Upstream product

• 80745-07-9 4-methoxy-2,3,6-trimethylbenzenesulfonyl chloride 
• 697-82-5 2,3,5-trimethylphenol 
• 20469-61-8 2,3,5-trimethylanisole 
• 80745-09-1 Z-Arg(Mtr)-OH*CHA 
• 80745-08-0 Z-Arg(Mtr)-OH 

Downstream Products

• 114645-16-8 Boc-Tyr(Bzl)-Arg(Mtr)-OH 
• 98930-01-9 Nα-(9-fluorenylmethoxycarbonyl)-Nγ-(4-methoxy-2,3,6-trimethylbenzenesulphonyl)-L-arginine 
• 143217-75-8 (S)-1-((R)-2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid [1-(3-guanidino-propyl)-2,5-dioxo-5-piperidin-1-yl-pentyl]-amide; compound with trifluoro-acetic acid 
• 143217-75-8 (S)-1-((S)-2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid [1-(3-guanidino-propyl)-2,5-dioxo-5-piperidin-1-yl-pentyl]-amide; compound with trifluoro-acetic acid 
• 143217-99-6 C₅₂H₆₅N₇O₉S 
• 143217-99-6 C₅₂H₆₅N₇O₉S 
• 143217-93-0 C₄₈H₅₈N₆O₁₀S 
• 143217-93-0 C₄₈H₅₈N₆O₁₀S 
• 143063-40-5 Fmoc-Thr(tBu)-Gln-Arg(Mtr)-Phe-OBzl 
• 143063-43-8 H-Glu(OtBu)-Thr(tBu)-Gln-Arg(Mtr)-Phe-OBzl 
• 143063-38-1 Fmoc-Gln-Arg(Mtr)-Phe-OBzl 
• 143063-41-6 H-Thr(tBu)-Gln-Arg(Mtr)-Phe-OBzl 
• 143063-39-2 H-Gln-Arg(Mtr)-Phe-OBzl 
• 143063-42-7 Fmoc-Glu(OtBu)-Thr(tBu)-Gln-Arg(Mtr)-Phe-OBzl 

Relevant articles and documents

SOLUTION SYNTHESIS OF THE HEPTADECAPEPTIDE SEQUENCE OF VESPULAKININ 1

Solution synthesis is described of the carbohydrate-free heptadecapeptide sequence of vespulakinin 1.The segment condensation strategy has been utilized to assemble the complete sequence.Carboxyl activation has been achieved by the 1-succinimidyl esters m

Further Studies on the Use of Multi-substituted Benzenesulfonyl Groups for Protection of the Guanidino Function of Arginine

Various multi-substituted benzenesulfonyl protecting groups for the guanidino function of arginine, removable under mild conditions such as with trifluoroacetic acid (TFA)-thioanisole, were studied.Among them, the 4-methoxy-2,6-dimethylbenzenesulfonyl (Mds) group, the 2,3,4,5,6-pentamethylbenzenesulfonyl (Pme) group, and the 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group were found to be useful.Both Mds and Pme show considerable resistance to TFA and, therefore, are suitable for procedures in which the intermediates are deprotected by TFA treatment, while Mtr is the most useful protecting group when TFA treatment is not necessary.Keywords---4-methoxy-2,6-dimethylbenzenesulfonyl (Mds); 2,4,6-trimethoxybenzenesulfonyl (Mtb); 2,3,4,5,6-pentamethylbenzenesulfonyl (Pme); 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); trifluoroacetic acid-thioanisole deprotection