80754-26-3

Basic information

• Product Name: ethyl 3-(4-hydroxy-2-methoxyphenyl)propanoate
• Synonyms: ethyl 3-(4-hydroxy-2-methoxyphenyl)propanoate
• CAS NO: 80754-26-3
• Molecular Weight: 0
• Mol File: 80754-26-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl 3-(4-hydroxy-2-methoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(4-hydroxy-2-methoxyphenyl)propanoate(80754-26-3)
• EPA Substance Registry System: ethyl 3-(4-hydroxy-2-methoxyphenyl)propanoate(80754-26-3)

Safety Data

• Hazardous Substances Data: 80754-26-3(Hazardous Substances Data)

Upstream product

• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 149968-37-6 ethyl (E)-3-(4-hydroxy-2-methoxyphenyl)acrylate 
• 149968-37-6 C₁₂H₁₄O₄ 
• 80754-22-9 ethyl 3-<2-hydroxy-4-(methoxymethoxy)phenyl>propanoate 
• 80754-21-8 7-(methoxymethoxy)-2H-chromen-2-one 
• 80754-23-0 ethyl 3-<2-methoxy-4-(methoxymethoxy)phenyl>propanoate 
• 73490-39-8 4-hydroxy-2-methoxy-trans-cinnamic acid 
• 114628-32-9 2-methoxy-4-(methoxylmethoxy)benzaldehyde 
• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 

Downstream Products

• 691902-35-9 3-{4-[(2',6'-dimethylbiphenyl-3-yl)methoxy]-2-methoxyphenyl}propanoic acid 
• 21144-18-3 3-(4-hydroxy-2-methoxyphenyl)-propanoic acid 
• 691902-34-8 ethyl 3-[4-[(2',6'-dimethylbiphenyl-3-yl)methoxy]-2-methoxyphenyl]propionate 

Relevant articles and documents

Ruthenium-catalyzed intramolecular arene C(sp2)-H amidation for synthesis of 3,4-dihydroquinolin-2(1 H)-ones

We report the [Ru(p-cymene)(l-proline)Cl] ([Ru1])-catalyzed cyclization of 1,4,2-dioxazol-5-ones to form dihydroquinoline-2-ones in excellent yields with excellent regioselectivity via a formal intramolecular arene C(sp2)-H amidation. The reactions of the 2- and 4-substituted aryl dioxazolones proceeds initially through spirolactamization via electrophilic amidation at the arene site, which is para or ortho to the substituent. A Hammett correlation study showed that the spirolactamization is likely to occur by electrophilic nitrenoid attack at the arene, which is characterized by a negative ρ value of -0.73.

Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent

We outline a simple protocol that accesses directly unprotected secondary amines by intramolecular C-N bond forming dearomatization or aryl C-H amination. The method is dependent on the generation of a potent electrophilic aminating agent released by in situ deprotection of O-Ts activated N-Boc hydroxylamines.

Phenyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.