807626-27-3

Upstream product

• 807626-23-9 1-ethyl-4-methyl-2-tert-butyldimethylsilyloxy-3-methylenebutanedioate 
• 108735-94-0 1-Ethyl 4-methyl 2-hydroxy 3-methylenebutanedioate 
• 807626-25-1 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 807626-30-8 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-tert-butyldimethylsilyloxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 267421-93-2 (3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidine 
• 807626-31-9 (3R,4R,1'S)-3-acetoxy-4-acetoxymethyl-1-(1'-phenylethyl)pyrrolidine 
• 859214-14-5 (3S,4S,1'S)-3-t-butoxycarbonylamino-4-(tetrahydropyran-2-yloxy)methyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-11-2 (3R,4R,1'S)-4-benzoyloxymethyl-3-methanesulfonyloxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-10-1 (3R,4R,1'S)-4-benzoyloxymethyl-3-hydroxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-45-2 (3S,4S,1'S)-3-t-butoxycarbonylamino-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-12-3 (3S,4S,1'S)-3-azido-4-benzoyloxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-13-4 (3S,4S,1'S)-3-azido-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-09-8 (3R,4R,1'S)-4-benzoyloxymethyl-3-t-butyldimethylsilyloxy-1-(1'-phenylethyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

Chiral 3-hydroxypyrrolidin-2-ones. Part 2: Stereodivergent synthesis of conformationally restricted analogues of β-homoserine

Starting from the homochiral 3-t-butyldimethylsilyloxypyrrolidin-2-one 2, a stereodivergent synthetic route was developed leading to both 3,4-trans- and 3,4-cis-3-amino-4-hydroxymethyl pyrrolidin-2-ones, 19 and 28, that are conformationally restricted ana

Chiral 3-hydroxypyrrolidin-2-ones from a Baylis-Hillman adduct: Convergent, stereoselective synthesis of a glycosidase inhibitor

The O-silyl derivative 4b, prepared starting from the Baylis-Hillman adduct 4a, underwent cyclization on treatment with (S)-phenylethylamine, to give to an equimolar mixture of the 4,5-cis-disubstituted pyrrolidin-2-ones 9 and 10, exclusively, which after