859214-45-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 807626-25-1 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 807626-27-3 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-09-8 (3R,4R,1'S)-4-benzoyloxymethyl-3-t-butyldimethylsilyloxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-11-2 (3R,4R,1'S)-4-benzoyloxymethyl-3-methanesulfonyloxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-10-1 (3R,4R,1'S)-4-benzoyloxymethyl-3-hydroxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-12-3 (3S,4S,1'S)-3-azido-4-benzoyloxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-13-4 (3S,4S,1'S)-3-azido-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 

Downstream Products

• 859214-14-5 (3S,4S,1'S)-3-t-butoxycarbonylamino-4-(tetrahydropyran-2-yloxy)methyl-1-(1'-phenylethyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

Chiral 3-hydroxypyrrolidin-2-ones. Part 2: Stereodivergent synthesis of conformationally restricted analogues of β-homoserine

Starting from the homochiral 3-t-butyldimethylsilyloxypyrrolidin-2-one 2, a stereodivergent synthetic route was developed leading to both 3,4-trans- and 3,4-cis-3-amino-4-hydroxymethyl pyrrolidin-2-ones, 19 and 28, that are conformationally restricted ana