807667-32-9

Upstream product

• 73260-77-2 2,3-Dichloro-benzenediazonium; chloride 
• 107-02-8 acrolein 

Downstream Products

• 302548-99-8 2-amino-5-(2,3-dichlorobenzyl)-1,3-thiazole 
• 327062-49-7 C₁₆H₁₁Cl₃N₂S 
• 327102-42-1 C₁₆H₁₂Cl₂N₂S 
• 292161-31-0 C₁₇H₁₄Cl₂N₂S 
• 302952-47-2 C₁₅H₁₁Cl₂N₃S 

Relevant academic research and scientific papers

Synthesis and antitumor activities of new n-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides

Aim. Synthesis of a series of new N-(5-benzyl-thiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides and study of their anticancer activity. Methods. Organic synthesis, analytical and spectral methods, pharmacological screening. Results. [2-chloro-N-(5-aryl-1,

Synthesis of heterocycles on the basis of products of arylation of unsaturated compounds 22.*3-Aryl-2-chloropropanal in the synthesis of N-Aryl-5-(R-benzyl)-1,3-thiazole-2-amines

3-Aryl-2-chloropropanal was obtained by the reaction of arenediazonium chlorides with acrolein in the presence of copper(II) chloride. N-Aryl(2-pyridyl)-5-(R-benzyl)-1,3-thiazole-2-amines were formed in high yield by the reaction of these aldehydes with a

Heterocyclic syntheses on the basis of arylation products of unsaturated compounds: X. 3-aryl-2-chloropropanals as reagents for the synthesis of 2-amino-1,3-thiazole derivatives

Meerwein reaction of arenediazonium chlorides with acrolein gave 3-aryl-2-chloropropanals which were brought into cyclocondensation with thiourea. The resulting 2-amino-5-benzyl-1,3-thiazoles were acylated with carboxylic acid chlorides and phthalic anhydride to afford, respectively, 2-acylamino-5-benzyl-1,3-thiazoles and N-(5-benzyl-1,3-thiazol-2-yl) phthalimides.