80783-14-8

Upstream product

• 17510-44-0 (1,2-dimethyl-propenyloxy)-trimethyl-silane 
• 7205-91-6 phenylthiomethyl chloride 

Downstream Products

• 214960-41-5 Acetic acid 2,2-dimethyl-1-methylene-3-phenylsulfanyl-propyl ester 
• 214960-55-1 (S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-eth-(E)-ylidene]-7-(4-methoxy-benzyloxy)-9-(2-methoxy-ethoxymethoxy)-2,2-dimethyl-1-phenylsulfanyl-nonan-3-one 
• 325706-83-0 (S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-eth-(Z)-ylidene]-7-(4-methoxy-benzyloxy)-2,2-dimethyl-1-phenylsulfanyl-8-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-octan-3-ol 
• 325706-75-0 (7S,9R,10R)-5-[(E)-2-tert-butyldiphenylsilyloxyethylidene]-7-(4-methoxybenzyloxy)-2,2-dimethyl-1-phenylsulfanyl-9,10-di-O-isopropylideneundecan-3-one 

Relevant academic research and scientific papers

Syntheses of C17-C27 fragments of 20-deoxybryostatins for assembly using Julia and metathesis reactions

Two approaches to the synthesis of compounds corresponding to the C17-C27 fragment of the 20-deoxybryostatins are described. The first approach is based on the palladium(0) catalysed coupling of tin enolates, generated in situ from enol acetates using tri

An approach to the C(17)-C(24) fragment of bryostatins: Applications of stereoselective trisubstituted alkene formation by palladium(0) catalysed coupling of enol acetates and vinylic bromides

The enol acetate 26 couples stereospecifically with the vinylic bromides 25 and 29 in the presence of tributyltin methoxide and a catalytic amount of dichlorobis(tri-o-tolylphosphine)palladium to give the βγ-unsaturated ketones 27 and 30 with retention of