808154-80-5

Basic information

• Product Name: [4-(3-{4-[(S)-2-(Bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-propoxy)-5-methoxy-2-nitro-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidin-1-yl]-methanone
• Synonyms: [4-(3-{4-[(S)-2-(Bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-propoxy)-5-methoxy-2-nitro-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidin-1-yl]-methanone
• CAS NO: 808154-80-5
• Molecular Weight: 937.089
• Mol File: 808154-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(3-{4-[(S)-2-(Bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-propoxy)-5-methoxy-2-nitro-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidin-1-yl]-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(3-{4-[(S)-2-(Bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-propoxy)-5-methoxy-2-nitro-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidin-1-yl]-methanone(808154-80-5)
• EPA Substance Registry System: [4-(3-{4-[(S)-2-(Bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-propoxy)-5-methoxy-2-nitro-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-4-difluoromethylene-pyrrolidin-1-yl]-methanone(808154-80-5)

Safety Data

• Hazardous Substances Data: 808154-80-5(Hazardous Substances Data)

Upstream product

• 808154-68-9 methyl (2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-4-difluoromethylidenepyrrolidine-2-carboxylate 
• 808154-70-3 (S)-1-(4-Benzyloxy-5-methoxy-2-nitro-benzoyl)-4-difluoromethylene-pyrrolidine-2-carbaldehyde 
• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 
• 64154-78-5 4-benzyloxy-5-methoxy-2-nitrobenzoyl chloride 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 
• 109-64-8 1,3-dibromo-propane 
• 808154-74-7 (2S)-N-(4-hydroxy-5-methoxy-2-nitrobenzoyl)-4-(difluoromethylidene)pyrrolidine-2-carboxaldehyde di(ethylthio)acetal 
• 102195-80-2 (S)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 
• 808154-66-7 methyl (2S)-4-difluoromethylidenepyrrolidine-2-carboxylate 
• 681283-18-1 methyl (2S)-N-tert-butoxycarbonyl-4-difluoromethyleneprolinate 
• 51-35-4 4R-4-hydroxyproline 

Relevant articles and documents

Synthesis of fluorinated analogues of SJG-136 and their DNA-binding potential

A series of C2-exo-fluorounsaturated pyrrolobenzodiazepines (PBDs) have been synthesized. These C2-exo-fluorounsaturated PBD dimers have exhibited remarkable DNA-binding affinity.