80865-96-9Relevant academic research and scientific papers
Stereochemistry of Sulphur Organic Compounds. Part 11. A Conformational Study of Some 2-Thio-derivatives of N-Phenyl-1-phenylethylamine
Brunet, Ernesto,Carreno, M. Carmen,Gallego, M. Teresa,Ruano, Jose L. Garcia,Alcudia, Felipe
, p. 937 - 942 (2007/10/02)
The syntheses and a conformational study of N-phenyl-2-Y-1-phenylethylamine +S(CH3)2> are reported.Conformational preferences have been established from changes in the vicinal coupling constant
β-Substituted Organolithium Compounds. Reaction with Alkyl Halides, Dimethyl Disulfide, and Imines
Barluenga, Jose,Fananas, Francisco J.,Villamana, Jorge,Yus, Miguel
, p. 1560 - 1564 (2007/10/02)
The reaction of β-substituted organolithium derivatives with several electrophiles leads to mono- as well as bifunctionalized organic compounds.Thus, by treatment of these dianions with alkyl halides a direct attack on the carbanionic carbon atom is performed, giving as a result substituted amines.When dimethyl disulfide is used, β-amino and β-hydroxy thioethers are obtained.Finally, on reaction with imines, 1-amino-3-hydroxy compounds and 1,3-diamines are obtained.Since these dianions are easily preparated by mercury-lithium transmetalation from β-substituted organomercurials resulting from the addition of mercury(II) salts to olefins, this whole process gives an appropriate way of functionalizing olefins.
