80867-18-1Relevant articles and documents
Ellipticine Derivatives with an Affinity to the Estrogen Receptor, an Approach to Develop Intercalating Drugs with a Specific Effect on the Hormone-Dependent Breast Cancer
Delbarre, Alain,Oberlin, Robert,Roques, Bernard P.,Borgna, Jean-Louis,Rochefort, Henri,et al.
, p. 752 - 761 (2007/10/02)
In order to obtain breast tumor directed agents, we have prepared mixed compounds using estradiol or (E)-clomiphene as specific vectors for the breast tissue and a DNA intercalator from the ellipticine series as cytotoxic agent.Among the newly synthesized