808739-71-1

Upstream product

• 1235-21-8 acetonyltriphenylphosphonium chloride 
• 147974-20-7 3-[4-(tert-butyl-dimethyl-silanyloxy)phenyl]propionaldehyde 

Downstream Products

• 808739-76-6 6-[4-(tert-butyldimethylsilyloxy)phenyl]-4-(1,3-dithiolan-2-ylmethyl)-4-[(4-methylphenyl)sulfonyl]hexan-2-one 
• 808739-74-4 2-(2-{2-[4-(tert-butyldimethylsilyloxy)phenyl]ethyl}-2-[(4-methylphenyl)sulfonyl]pent-4-yl)-2-methyl-1,3-dioxolane 
• 808739-75-5 5-[4-(tert-butyldimethylsilyloxy)phenyl]-3-(2-methyl-1,3-dioxolan-2-ylmethyl)-3-[(4-methylphenyl)sulfonyl]pentanal 
• 808739-77-7 3-{2-[4-(tert-butyldimethylsilyloxy)phenyl]ethyl}-5-oxo-3-[(4-methylphenyl)sulfonyl]hexanal 
• 808739-73-3 2-({4-[4-(tert-butyldimethylsilyloxy)phenyl]}-2-[(4-methylphenyl)sulfonyl]butyl)-2-methyl-1,3-dioxolane 
• 808740-95-6 3-[2-(4-tert-butyldimethylsilyloxy)phenyl]ethyl-5-hydroxycyclohex-2-enone 
• 808739-72-2 6-[4-(tert-butyldimethylsilyloxy)phenyl]-4-[(4-methylphenyl)sulfonyl]hexan-2-one 

Relevant academic research and scientific papers

First total synthesis of (±)-prelunularin

The first total synthesis of (±)-prelunularin is described employing an intramolecular aldol addition/sulfinate elimination tandem reaction. Investigations on the mechanism of the one-pot cyclization reaction using time-dependent NMR spectroscopy suggested that the sulfinate elimination took place before the intramolecular ring-closing aldol addition.