808740-33-2 Usage
Description
3-(2-Methoxy-phenyl)-isoxazole-5-carbaldehyde is a chemical compound characterized by its molecular formula C10H9NO3. It is an isoxazole derivative, featuring a five-membered heterocyclic ring that includes oxygen and nitrogen atoms. 3-(2-METHOXY-PHENYL)-ISOXAZOLE-5-CARBALDEHYDE is distinguished by its functional aldehyde group and the presence of a methoxy group and a phenyl ring, which contribute to its reactivity and potential biological activity. It is widely recognized in the fields of organic synthesis and medicinal chemistry research for its versatility as a building block in the creation of a variety of organic molecules.
Uses
Used in Organic Synthesis:
3-(2-Methoxy-phenyl)-isoxazole-5-carbaldehyde is utilized as a key intermediate in organic synthesis for the preparation of complex organic molecules. Its aldehyde group allows for a range of reactions, making it a valuable component in the construction of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 3-(2-Methoxy-phenyl)-isoxazole-5-carbaldehyde is employed as a building block for the development of potential pharmaceuticals. 3-(2-METHOXY-PHENYL)-ISOXAZOLE-5-CARBALDEHYDE's structure, including the methoxy and phenyl groups, can influence its interaction with biological targets, thus contributing to its potential as a therapeutic agent.
Used in the Development of Agrochemicals:
3-(2-Methoxy-phenyl)-isoxazole-5-carbaldehyde also finds application in the agrochemical industry. Its specific reactivity and the possibility of fine-tuning its properties through chemical modifications make it a candidate for the development of new pesticides or other agrochemical products.
Used in Chemical Research and Development:
3-(2-METHOXY-PHENYL)-ISOXAZOLE-5-CARBALDEHYDE is also used in academic and industrial research settings to explore new chemical reactions and to develop novel synthetic routes. Its unique structure and reactivity make it a subject of interest for scientists looking to innovate in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 808740-33-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,0,8,7,4 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 808740-33:
(8*8)+(7*0)+(6*8)+(5*7)+(4*4)+(3*0)+(2*3)+(1*3)=172
172 % 10 = 2
So 808740-33-2 is a valid CAS Registry Number.
808740-33-2Relevant articles and documents
A rapid and efficient solvent-free microwave-assisted synthesis of pyrazolone derivatives containing substituted isoxazole ring
Zhang, Dawei,Zhang, Yumin,Zhao, Tianqi,Li, Jing,Hou, Yaya,Gu, Qiang
, p. 2979 - 2987 (2016/05/19)
An efficient synthesis of 4-substituted pyrazolone derivatives was developed. 4-Substituted pyrazolone derivatives were synthesized in 78-97% yields starting from various 3-substituted isoxazole-5-carbaldehydes, ethyl acetoacetate and hydrazine under micr
Efficient solvent-free synthesis of bis(indolyl)methanes on SiO2 solid support under microwave irradiation
Zhang, Da-Wei,Zhang, Yu-Min,Zhang, Yi-Liang,Zhao, Tian-Qi,Liu, Hong-Wei,Gan, Yuan-Ming,Gu, Qiang
, p. 470 - 478 (2015/01/30)
An efficient synthesis of bis(indolyl)methanes was developed. Bis(indolyl)methanes were synthesized starting from various aromatic aldehydes with indole under microwave irradiation and solvent-free conditions (85-98 %). Solid support SiO2 was found to possess favorable catalytic and dispersancy parameters for the condensation reaction. Moreover, novel bis(indolyl)methanes containing an isoxazole ring were synthesized via this method in excellent yields (> 94 %) using 3-substituted isoxazole-5-carbaldehydes and indole.
Synthesis and biological evaluation of novel T-type Ca2+ channel blockers
Jung, Hee Kyung,Doddareddy, Munikumar Reddy,Cha, Joo Hwan,Rhim, Hyewhon,Cho, Yong Seo,Koh, Hun Yeong,Jung, Bong Young,Pae, Ae Nim
, p. 3965 - 3970 (2007/10/03)
A small molecule library of piperazinylalkylisoxazole derivatives containing about 600 compounds was designed, synthesized and evaluated for blocking effects on T-type Ca2+ channel. Several ligands were identified to possess high inhibitory activity against the T-type Ca 2+ channel. The compound 21 with trifluoromethyl substituents at C3-position of phenyl group (R1) and C2- position of phenyl group (R2) showed the highest inhibitory activity with IC50 value of 1.02μM, which is comparable to that of mibefradil.
