80900-55-6

Upstream product

• 22833-69-8 methyl 6-methoxysalicylate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 80900-56-7 2-(tert-Butyl-dimethyl-silanyloxy)-6-methoxy-1-(3-trimethylsilanyloxy-pentyl)-cyclohexa-2,5-dienecarboxylic acid methyl ester 
• 108161-81-5 methyl 2-(t-butyldimethylsiloxy)-1-(3'-hydroxypentyl)-6-methoxy-2,5-cyclohexadiene-1-carboxylate 
• 80900-60-3 2-(tert-Butyl-dimethyl-silanyloxy)-6-methoxy-1-(3-oxo-butyl)-cyclohexa-2,5-dienecarboxylic acid methyl ester 
• 80900-57-8 methyl 2-(t-butyldimethylsiloxy)-6-methoxy-1-(3'-oxopentyl)-2,5-cyclohexadiene-1-carboxylate 

Relevant academic research and scientific papers

IMPROVED METHODS FOR THE REDUCTIVE ALKYLATION OF METHOXYBENZOIC ACIDS AND ESTERS: APPLICATION TO THE SYNTHESIS OF BICYCLIC KETONES

A series of methoxybenzoic acids and esters was reduced by metal-ammonia solutions and the resulting 1,4-dihydro products were either alkylated subsequently.Three different types of alkyl iodies were employed to introduce the elements of a butanone or pentanone side-chain as a prelude to adding a fused six-membered ring, thereby completing the preparation of several analogues of the Wieland-Miescher ketone 4a in which the angular substituent was oxygenated.