80900-56-7Relevant academic research and scientific papers
STUDIES ON REDUCTIVE ALKYLATION: SYNTHESIS OF WIELAND-MIESCHER KETONE ANALOGUES BEARING AN OXYGENATED ANGULAR SUBSTITUENT
Mander, L. N.,Hamilton, R. J.
, p. 4115 - 4118 (1981)
Wieland-Miescher analogues 2a and 2b have been prepared in good yield by a sequence utilising reductive alkylation of the dihydro aromatic ester enolate 7d, which functions as a synthetic equivalent of the dioxo ester 5 anion; these analogues are envisaged as intermediates in a projected synthesis of bruceantin.
