80907-18-2Relevant academic research and scientific papers
Inexpensive Radical Methylation and Related Alkylations of Heteroarenes
Huang, Qi,Zard, Samir Z.
supporting information, p. 1413 - 1416 (2018/03/09)
A simple method for the introduction of a methyl and higher aliphatic group to various heteroarenes using very inexpensive reagents is described. It is based on the radical addition of a carboxylic xanthate followed by decarboxylation. Depending on the heteroarene structure, the decarboxylation can be spontaneous or induced by heating in N,N-dimethylacetamide or N-methyl pyrrolidone in a microwave oven.
3-Substituted Flavones. 1. Reduction of and Conjugate Addititon to (E)-2-Methoxy-3-(carbethoxymethylene)flavones
Smith, Manning A.,Klebanoff, Leonard E.,Morrow, Christopher T.,Sandel, Bonnie B.
, p. 1702 - 1706 (2007/10/02)
The methyl 3-hemiketal of 2-methoxy-3,4-flavandiones 3 react readily with the ylide ethyl (triphenylphosphoranylidene)acetate 12 to form (E)-2-methoxy-3-(carbethoxymethylene)flavanones 4.Compounds 4 are readily reduced by zinc and acetic acid to form the
