80914-29-0Relevant academic research and scientific papers
Thiocarbonyl Olefination, IV. - Preparation of β-Amino Acids from N-(Acetyl)thioamides; Total Synthesis of Iturinic Acid
Slopianka, Marion,Gossauer, Albert
, p. 2258 - 2265 (2007/10/02)
A new method for the synthesis of β-amino acids is described whose key step consists in the regioselective thiocarbonyl olefination of N-(acetyl)thioamides with methyl (triphenylphosphoranylidene)acetate.By this procedure, a straightforward synthesis of iturinic acid has been carried out for the first time.
