809231-58-1Relevant articles and documents
Continuous flow Sonogashira C-C coupling using a heterogeneous palladium-copper dual reactor
Tan, Li-Min,Sem, Zhi-Yu,Chong, Wei-Yuan,Liu, Xiaoqian,Hendra,Kwan, Wei Lek,Lee, Chi-Lik Ken
supporting information, p. 65 - 67 (2013/03/28)
We report the development of a heterogeneous catalyst system on continuous flow chemistry. A palladium (Pd) coated tubular reactor was placed in line with copper (Cu) tubing using a continuous flow platform, and a Sonogashira C-C coupling reaction was used to evaluate the performance. The reactions were favorably carried out in the Cu reactor, catalyzed by the traces of leached Pd from the Pd reactor. The leached Pd and Cu were trapped with a metal scavaging resin at the back-end of the continuous flow system, affording a genuine approach toward green chemistry.
Acyclic diaminocarbenes: Simple, versatile ligands for cross-coupling reactions
Dhudshia, Bhartesh,Thadani, Avinash N.
, p. 668 - 670 (2008/02/10)
Acyclic diaminocarbenes are found to be useful ligands for palladium catalyzed Suzuki-Miyaura, Sonogashira and Heck cross-coupling reactions of aryl/alkenyl bromides and chlorides. The Royal Society of Chemistry 2006.