809238-56-0Relevant academic research and scientific papers
Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)
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, (2008/06/13)
The present invention provides compounds of Formula (I): or a stereoisomer or pharmaceutically acceptable salt form thereof, wherein the variables L, Z0, R1, R4, R5, and R11 are defined are as defined herein, which are useful as inhibitors of matrix metalloproteinases (MMP), TNF-α converting enzyme (TACE), aggrecanase, or a combination thereof.
