80980-09-2Relevant academic research and scientific papers
Synthesis and QSAR studies of some novel disubstituted 1,2,4-triazoles as antimicrobial agents
Panda, Siva S.,Jain, Subhash C.
, p. 848 - 861 (2014)
Disubstituted 1,2,4-triazoles 3a-k, 4a-k, and 6a-k have been synthesized from anthranilic acid and nicotinic acid, respectively, through a multi-step reaction sequence via their hydrazides. Synthesized compounds were evaluated for their in vitro antimicro
Synthesis and analgesic activity of new pyridine-based heterocyclic derivatives
Nigade, Ganesh,Chavan, Pradeep,Deodhar, Meenakshi
experimental part, p. 27 - 37 (2012/06/01)
A series of new heterocyclic derivatives having a pyridine nucleus were synthesized. 4-(5-(2-Chlorophenyl)- 4H-1,2,4-triazol-3-yl)pyridine (7c) and 4-(5-(2- Nitrophenyl)-4H-1,2,4-triazol-3-yl)pyridine (7d) presented the best analgesic profie of this series in hot-plate, tail-flick, and formalin-induced licking tests, which was partially prevented by pretreatment with mecamylamine, a nicotinic receptor antagonist. Springer Science+Business Media, LLC 2010.
Metallhydrazide, XIX. Addition bis(diethylaluminio)substituierter Amidrazone und Carbohydrazide an Nitrile
Kauffmann, Thomas,Ban, Laszlo,Kuhlmann, Dieter
, p. 3684 - 3690 (2007/10/02)
Amidrazones and carbohydrazides react with two equivalents of triethylaluminium to give bis(diethylaluminio) derivatives 1 and 7, respectively.In contrast to the corresponding mono(diethylaluminio) derivatives or disodium salts, these are capable of addit
