80992-66-1Relevant academic research and scientific papers
Titanium as a Regio- and Stereo-selective Control Element in the Reaction of α-Alkoxyallylic Phosphine Oxide Anions with Carbonyl Compounds
Birse, Ewan F.,McKenzie, Alexander,Murray, Alistair W.
, p. 1039 - 1046 (2007/10/02)
A general method is described for directing the condensation of α-methoxyallylphosphine oxide anions (2) with aldehydes, preferentially at the α-position of the allyl system.The procedure, which employs the formation of the titanium ate complex, yields pure diastereoisomers with high stereoselectivity, and these can be used in Horner-Wittig reactions to provide an efficient and convenient synthesis of conjugated methoxydienes of defined geometry.Under the same conditions, acyl halides yield γ-adducts.
REGIOCHEMISTRY OF REACTIONS OF α-ALKOXYALLYLPHOSPHINE OXIDE YLIDES WITH ELECTROPHILES.
Maleki, Mehran,Miller, J. Allen,Lever, O. William
, p. 3789 - 3792 (2007/10/02)
Anions 4, derived from α-methoxyallylphosphine oxides 3, react with electrophiles in a highly regioselective fashion to give products of α-attack or γ-attack depending upon the substitution pattern of the ylid 4 and the nature of the electrophile.
