80998-63-6Relevant academic research and scientific papers
Nickel-Catalyzed Dearomative Arylboration of Indoles: Regioselective Synthesis of C2- And C3-Borylated Indolines
Brown, M. Kevin,Crook, Phillip F.,Kuniyil, Rositha,Liu, Peng,Trammel, Grace L.
supporting information, p. 16502 - 16511 (2021/10/20)
Indole dearomatization is an important strategy to access indolines: a motif present in a variety of natural products and biologically active molecules. Herein, a method for transition-metal catalyzed regioselective dearomative arylboration of indoles to
A indole compound and its preparation method and application (by machine translation)
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Paragraph 0059; 0074; 0075, (2018/10/02)
The invention discloses a indole compound and its preparation method and application. The indole compounds of the structural formula such as formula (I) is shown. The indoles, rice galenical demonstrate the excellent inhibitory activity, the effect of most of the compound is obviously better than the positive control drug validamycin; especially compound I - 43, I - 44, I - 54, I - 73, II - 7 and II - 17, its galenical very good living body protection and treating effect, effect is better than the positive control; more specifically, compound I - 43 of the rice sheath blight bacteriostatic activity than validamycin activity is improved by nearly 300 times. The indole compounds in the prevention and/or treatment of rice sheath blight has great application prospects. In addition the compound of the invention is simple in construction, the preparation method is simple, and is suitable for large-scale industrial production. (I). (by machine translation)
A Direct Access to 7-Aminoindoles via Iridium-Catalyzed Mild C-H Amidation of N-Pivaloylindoles with Organic Azides
Kim, Youyoung,Park, Juhyeon,Chang, Sukbok
supporting information, p. 1892 - 1895 (2016/05/19)
Ir(III)-catalyzed regioselective direct C-7 amidation of indoles in reaction with organic azides has been developed. While its efficiency was varied by the choice of N-directing groups, N-pivaloylindoles were most effective in undergoing the desired amidation at room temperature over a broad range of substrates. The reaction was scalable, and deprotection of the chelation group was also facile.
Single-flask synthesis of N-acylated indoles by catalytic dehydrogenative coupling with primary alcohols
Maki, Brooks E.,Scheidt, Karl A.
supporting information; experimental part, p. 1651 - 1654 (2009/09/06)
Indoles and alcohols can be coupled in a dehydrogenative process catalyzed by tetrapropylammonium perruthenate. This efficient approach to indolylamides proceeds in a single flask under mild conditions. By employing substituted indoles and alkyl, branched
SYNTHESIS AND SOME PROPERTIES OF 1H-1-BENZAZEPINES
Ikeda, Masazumi,Ohno, Kazunori,Uno, Toshiko,Tamura, Yasumitsu
, p. 3403 - 3406 (2007/10/02)
1H-1-Benzazepines were synthesized by thermal ring opening of 2a, 7b-dihydrocyclobutindoles.The thermal and photochemical behavior of the 1H-1-benzazepines is also described.
