81-54-9

Usage

Uses

Used in Herbal Remedies:
Purpurin is used as a herbal remedy for its potential health benefits derived from its antioxidant properties and ability to inhibit serine protease.
Used in Food Coloring:
Purpurin is used as a natural food coloring agent due to its reddish-yellow pigmentation.
Used in Cotton Printing Dyes:
Purpurin is used as a color pigment in cotton printing dyes, taking advantage of its natural color and historical use in dyeing.
Used as a Xanthine Oxidase Inhibitor:
Purpurin is used as a xanthine oxidase inhibitor, which can help in managing conditions related to purine metabolism.
Used in Antioxidant Applications:
Due to its high antioxidant activity, purpurin is used as a potential radical scavenger to protect against oxidative stress and related health issues.
Used in Enzyme Inhibition:
Purpurin is used as an inhibitor of serine protease, which can have implications in various biological processes and disease conditions.

Purification Methods

Crystallise purpurin from aqueous EtOH, dry it at 100o. [Beilstein 8 IV 3568.]

InChI:InChI=1/C14H8O5/c15-8-5-9(16)14(19)11-10(8)12(17)6-3-1-2-4-7(6)13(11)18/h1-5,15-16,19H

Upstream product

• 85-44-9 phthalic anhydride 
• 95-57-8 2-monochlorophenol 
• 95-77-2 3,4-dichlorophenol 
• 95-88-5 4-Chlororesorcinol 
• 106-48-9 4-chloro-phenol 
• 1709-63-3 anthracene-1,4,9,10-tetraone 
• 81-64-1 1,4-dihydroxy-9,10-anthracenedione 
• 72-48-0 1,2-dihydroxy-9,10-anthracenedione 
• 81-52-7 2-bromoquinizarine 
• 476-41-5 pseudopurpurin 
• 2835-53-2 4-amino-1,2-dihydroxy-anthraquinone 
• 26687-60-5 1,4-Dihydroxy-2-amino-9,10-anthracenedione 
• 84-65-1 9,10-phenanthrenequinone 
• 120-12-7 anthracene 

Downstream Products

• 67905-10-6 8-hydroxy-6,15-dihydro-dinaphtho[2,3-a;2',3'-h]phenazine-5,9,14,18-tetraone 
• 120-12-7 anthracene 
• 81-64-1 1,4-dihydroxy-9,10-anthracenedione 
• 61169-36-6 1,2,4,5,6,8-hexahydroxy-9,10-anthraquinone 
• 2246-48-2 2-acetyl-3-hydroxy-1,4-naphthoquinone 
• 857555-58-9 3-(3-hydroxy-1,4-dioxo-1,4-dihydro-[2]naphthyl)-3-oxo-propionic acid 
• 476-41-5 pseudopurpurin 
• 81-51-6 1-amino-2,4-dihydroxy-anthraquinone 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 4644-05-7 1,4-dihydroxy-2-p-toluidino-anthraquinone 
• 615-94-1 2,5-dihydroxy-1,4-benzoquinone 
• 361148-73-4 HRu(CO)(P(C₆H₁₁)3)2(C₁₄H₅O₅H₂) 
• 361148-72-3 Ru(CO)2(P(C₆H₁₁)3)2(C₁₄H₅O₅H) 
• 16517-84-3 Toluene-4-sulfonic acid 1,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracen-2-yl ester 

Relevant academic research and scientific papers

METHOD FOR PREPARING ALIZARIN DERIVATIVE COMPOUND, NOVEL ALIZARIN DERIVATIVE COMPOUND, SURFACE MODIFICATION METHOD, PHOTOELECTRIC CONVERSION FILM, PHOTOELECTRIC CONVERSION ELEMENT, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR

The present invention provides a novel alizarin derivative compound and a simplified and low cost method for preparing an alizarin derivative compound including: obtaining a compound represented by Formula (2) using a compound represented by Formula (3); and obtaining an alizarin derivative compound represented by Formula (1) using the compound represented by Formula (2); in Formulae (1) to (3), R1 represents a hydrogen atom or a substituent; n represents an integer of 1 to 3, L represents a specific alkyl group; Q represents an atomic group needed to form an aromatic ring or a heteroaromatic ring with adjacent carbon atoms; and P represents an atomic group which includes an atom(s) selected from a hydrogen atom, a carbon atom, an oxygen atom, a sulfur atom, a silicon atom and a boron atom, and which is needed to form a ring structure group with adjacent two oxygen atoms and two carbon atoms; Formula (1) Formula (2) Formula (3).

Pathway of anthracene modification under simulated solar radiation

Exposure of polycyclic aromatic hydrocarbons (PAHs) to sunlight results in rapid structural photomodification generally via oxidation reactions. These PAH modification products are in many cases more toxic than their parent compounds. In this study, anthracene (ANT), a rapidly photooxidized PAH, was irradiated with simulated solar radiation (SSR, 100 μmol m-2 s- 1) in aqueous solution to examine the photomodification pathway. The photoproducts formed were identified by HPLC. The ANT product profile after 9 h in SSR was very complex, with more than 20 compounds detected. The photoproducts formed were anthraquinones, benzoic acids, benzaldehydes and phenols showing the process to be oxidative in nature. Some of the anthraquinones were themselves subject to photooxidation, and were thus intermediates in the product pathway. The kinetics of ANT photooxidation revealed a pseudo first-order reaction with a half-life of 2 h under the SSR source used. The kinetics of product formation allowed deduction of a probable photomodification pathway. This study indicates that PAH photooxidation products are likely to exist as complex, dynamically changing mixtures in PAH contaminated aquatic environments.

Method for dyeing keratinous fibres using a monohydroxyindole or dihydroxyindole and a non-oxidizing aromatic carbonyl derivative and dyeing agent

The present invention relates to a method for dyeing keratinous fibers, characterized in that the following are applied to the fibers: a) a composition (A) containing, in a medium appropriate for dyeing, at least one monohydroxyindole or dihydroxyindole, this application being preceded or followed by the application of b) a composition (B) containing, in a medium appropriate for dyeing, at least one aromatic carbonyl derivative chosen from hydroxyacetophenones, hydroxybenzophenones, 2-hydroxy-1,4-benzoquinones, hydroxy-1,4-naphthoquinones,amino-1,4-naphthoquinones,hydroxy-9,10-anthraquinones and amino-9,10-anthraquinones. It also relates to the dyeing agents for carrying it out.

Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions

Families of chlorins, families of purpurins and metal complexes thereof are disclosed. The purpurins and their metal complexes have the structures of FIGS. 1, 7, 14-18, 29-38, 44-48 and 54-58 of the attached drawings. The chlorins and their metal complexes have the formulas of FIGS. 2, 8, 19, 20, 22, 23, 24, 25, 27, 28, 39, 40, 42, 43 and 49-53 of the attached drawings. Solutions of the purpurins, of the foregoing and other chlorins and of the metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil. A method for detecting and treating tumors in human and animal patients is also disclosed. The method comprises administering one of the purpurins, chlorins or metal complexes to the patient. For detection, the patient is then illuminated with ultra violet light; for treatment, the patient is illuminated with visible light of a wavelength at which the purpurin, chlorin or complex administered shows an absorption peak. Families of purpurins, chlorins and metal complexes which can be detected by nuclear magnetic resonance or by an instrument that detects ionizing radiation are also disclosed. These compounds have the formula of one of FIGS. 1, 2, 7, 8, or 14-58 and a structure which is enriched in an atom that can be detected by nuclear magnetic resonance, e.g., C-13 or N-15, or by an instrument that detects ionizing radiation, e.g., C-14.

Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions

Families of chlorins, families of purpurins and metal complexes thereof are disclosed. The purpurins and their metal complexes have the structures of FIGS. 1, 7, 14-18, 29-38, 44-48 and 54-58 of the attached drawings. The chlorins and their metal complexes have the formulas of FIGS. 2, 8, 19, 20, 22, 23, 24, 25, 27, 28, 39, 40, 42, 43 and 49-53 of the attached drawings. Solutions of the purpurins, of the foregoing and other chlorins and of the metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil. A method for detecting and treating tumors in human and animal patients is also disclosed. The method comprises administering one of the purpurins, chlorins or metal complexes to the patient. For detection, the patient is then illuminated with ultra violet light; for treatment, the patient is illuminated with visible light of a wavelength at which the purpurin, chlorin or complex administered shows an absorption peak. Families of purpurins, chlorins and metal complexes which can be detected by nuclear magnetic resonance or by an instrument that detects ionizing radiation are also disclosed. These compounds have the formula of one of FIGS. 1, 2, 7, 8, or 14-58 and a structure which is enriched in an atom that can be detected by nuclear magnetic resonance, e.g., C-13 or N-15, or by an instrument that detects ionizing radiation, e.g., C-14.

Production and use of dimers of hematoporophyrin, purpurins, chlorines and purpurin- and chlorin-complexes

Dimers which are either esters or amides of (1) a purpurin, a chlorin or a metal complex and (2) hematoporphyrin or a purpurin, a chlorin or a metal complex are disclosed. The purpines and their metal complexes have the structures of FIGS. 1, 7, 14-18, 29-38, 44-48 and 54-58 of the attached drawings. The chlorins and their metal complexes have the formulas of FIGS. 2, 8, 19-28, 39-43 or 49-53 of the attached drawings. Solutions of the purpurins, chlorins and metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil. A method for detecting and treating tumors in human and animal patients is also disclosed. The method comprises administering one of the dimers to the patient. For detection, the patient is then illuminated with ultra violet light; for treatment, the patient is illuminated with visible light of a wavelength at which the purpurin, chlorin or complex administered shows an absorption peak or with X rays or other ionizing radiation. Dimers of purpurins, chlorine and metal complexes which can be detected by nuclear magnetic resonance or by an instrument that detects ionizing radiation are also disclosed. The purpurins, chlorins and coplexers of these dimers have the formula of one of FIGS. 1, 2, 7, 8, or 14-58 and a structure which is enriched in an atom that can be detected by nuclear magnetic resonance, e.g., C-13 or N-15, or by an instrument that detects ionizing radiation, e.g., C-14, I-131 or Tc-99m.