81019-10-5Relevant academic research and scientific papers
Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
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, (2008/06/13)
A series of novel polypeptide derivatives, containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues, which are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin. Particularly valuable precursors for many of these compounds are certain other 5-amino-2,5-disubstituted-4-hydroxypentanoic acid derivatives.
