81028-07-1

Upstream product

• 78469-77-9 (4S,5S)-4-benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-1,3-dioxolane 
• 502481-96-1 (2S,3R)-4-benzyloxy-2,3-(propane-2,2-dioxy)-1-butanol 
• 78492-30-5 (2S,3S)-4-benzyloxy-1,2,3-butanetriol 
• 78513-07-2 ((2R,3S)-3-((benzyloxy)methyl)oxiran-2-yl)methanol 
• 81028-03-7 (Z)-4-benzyloxy-but-2-en-1-ol 
• 81028-04-8 (2R,3S)-1-Benzyloxy-4-phenylsulfanyl-butane-2,3-diol 
• 81028-06-0 Phenyl-carbamic acid (2R,3S)-3-benzyloxymethyl-oxiranylmethyl ester 
• 81028-05-9 Acetic acid ((4R,5R)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-phenylsulfanyl-methyl ester 
• 127896-23-5 4-benzyloxy-2,3-O-isoproylidene-L-threitol 

Downstream Products

• 885041-19-0 4-benzyloxy-1,2,3-tri(tert-butyldimethylsilyloxy)-L-threitol 
• 2319-57-5 threitol 
• 78492-30-5 (2S,3S)-4-benzyloxy-1,2,3-butanetriol 

Relevant academic research and scientific papers

Ophthamological drugs

The present invention relates generally to ophthamological drugs. More specifically, the inventon relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to d

[(Z)-γ-[(diisopropylidene-α-D-mannopyranosyl)oxy]allyl]- tributylstannane: A new chiral reagent for the asymmetric α-hydroxyallylation of aldehydes

Reactions of [(Z)-γ- [(diisopropylidene-α-D-mannopyranosyl)oxy]allyl]tributylstannane (6) with several chiral and achiral aldehydes are described. This reagent was designed in anticipation that significant diastereofacial bias in reactions with aldehydes

Regioselective protection of triols to cyclic carbonates

Regioselective protection of 1,2,3-, 1,2,4-, and 1,2,5-triols to 5- membered cyclic carbonates with triphosgene, dimethyl carbonate, or carbonyldiimidazole is described.

Synthesis of Saccharides and Related Polyhydroxylated Natural Products. 1. Simple Alditols

A new approach to sugar synthesis is demonstrated through syntheses of tetritols, pentitols, and hexitols; titanium-catalyzed asymmetric epoxidation and a new selective opening reaction of 2,3-epoxy alcohols play essential roles.