81050-04-6

Usage

Uses

Used in Coordination Chemistry:
(4-methoxy-phenethyl)-thiourea is used as a ligand for forming complexes with metal ions, which is beneficial for [application reason]. This property makes it a valuable compound in the field of coordination chemistry.
Used in Medicine:
(4-methoxy-phenethyl)-thiourea is used as a potential pharmaceutical compound for [application reason], such as targeting specific metal ion interactions in the body that may be related to certain diseases or conditions.
Used in Agriculture:
In the agricultural industry, (4-methoxy-phenethyl)-thiourea is used as a potential agent for [application reason], possibly involving the interaction with metal ions in the soil or within plants to enhance growth or protect against certain conditions.
Used in Material Science:
(4-methoxy-phenethyl)-thiourea is used as a component in the development of new materials for [application reason], such as creating metal ion-based sensors or developing materials with specific electronic or magnetic properties.

Upstream product

• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 566163-53-9 C₁₇H₁₈N₂O₂S 
• 1147550-11-5 ammonium thiocyanate 
• 55-81-2 4-Methoxyphenethylamine 

Downstream Products

• 1134178-07-6 4-[(4-n-butyl)phenyl]-2-[N-(2-(4-methoxyphenyl)ethyl)amino]thiazole 
• 1134178-11-2 4-[(4-tert-butyl)phenyl]-2-[N-(2-(4-methoxyphenyl)ethyl)amino]thiazole 
• 1134178-09-8 4-[(4-iso-butyl)phenyl]-2-[N-(2-(4-methoxyphenyl)ethyl)amino]thiazole 
• 1222375-90-7 C₁₃H₁₅N₃O₂S 

Relevant academic research and scientific papers

Synthesis, SAR and docking studies of substituted aryl phenylthiazolyl phenylcarboxamide as potential protein tyrosine phosphatase 1B (PTP1B) inhibitors

In our continued effort to discover novel PTP1B inhibitor with improved in vivo activity, we attempted to optimize our previously discovered lead compound by replacing the sulfonyl group with benzoyl group to yield compound II. Additional structural modif

Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators

Pompe disease is a lysosomal storage disease (LSD) caused by a deficiency in the lysosomal enzyme acid alpha-glucosidase. In several LSDs, enzyme inhibitors have been used as small molecule chaperones to facilitate and increase the translocation of mutant protein from the endoplasmic reticulum to the lysosome. Enzyme activators with chaperone activity would be even more desirable as they would not inhibit the enzyme after translocation and might potentiate the activity of the enzyme that is successfully translocated. Herein we report our initial findings of a new series of acid alpha-glucosidase activators.

Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: Synthesis, pharmacological evaluation, and cross-target QSAR studies

Previous studies have demonstrated that clobenpropit (N-(4-chlorobenzyl)-S-[3-(4(5)-imidazolyl)propyl]isothiourea) binds to both the human histamine H3 receptor (H3R) and H4 receptor (H4R). In this paper, we describe the synthesis and pharmacological characterization of a series of clobenpropit analogs, which vary in the functional group adjacent to the isothiourea moiety in order to study structural requirements for H3R and H4R ligands. The compounds show moderate to high affinity for both the human H3R and H4R. Furthermore, the changes in the functional group attached to the isothiourea moiety modulate the intrinsic activity of the ligands at the H4R, ranging from neutral antagonism to full agonism. QSAR models have been generated in order to explain the H3R and H4R affinities.

Bismuth chloride mediated synthesis, antimicrobial, and anti-inflammatory activities of new 4-aryl-2-amino thiazoles

Synthesis of 4-aryl-2-Amino thiazoles (3a-u), (4a-c), and (5a-c) was achieved from the reaction of 4-butyl phenacyl chlorides (2a-c) with N-substituted thioureas, in the presence of Bismuth Chloride. The antimicrobial and anti-inflammatory activities of the final products were also studied. Copyright Taylor & Francis Group, LLC.