81054-32-2Relevant academic research and scientific papers
Efficient synthesis of N-methylamides and amines via 4-(alkylamino)benzyl- N-methylamine as a new protecting group
Lee, Sang-Hak,Mu, Yu,Kim, Gun-Woo,Kim, Jin-Seok,Park, Seok-Hwi,Jin, Tian,Lee, Kee-Young,Ham, Won-Hun
, p. 1749 - 1764 (2013/09/12)
4-(Alkylamino)benzyl-N-methylamine is a good protecting group for the synthesis of N-methylamides and amines. The N-debenzylation of N-methylamides and amines can be carried out selectively and efficiently under condition using trifluoroacetic acid (TFA).
Amino- and Amidomethylation of N,N-Dimethylaniline and Related Derivatives
Boehme, Horst,Bomke, Ulrich,Denis, Jean-Pierre
, p. 40 - 47 (2007/10/02)
The reaction of N,N-dimethylaniline (4) with N-methylenemorpholinium chloride (10g) affords 2,4-bis(morpholinomethyl)-N,N-dimethylaniline (11g) via 4-(morpholinomethyl)-N,N-dimethylaniline (9g) as an intermediate.From 4-(dimethylaminomethyl)- or 4-(pyrrol
