81086-92-2

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 57-50-1 Sucrose 

Downstream Products

• 303779-98-8 6,6'-di-O-tert-butyldiphenylsilyl-1'-O-tert-butyldimethylsilylsucrose 
• 790685-10-8 1'-O-TBDMS-6,6'-di-O-TBDPS-2,3,3',4,4'-penta-O-acetyl-sucrose 
• 81086-98-8 6,6'-di-O-tert-butyldiphenylsilyl-2,3,4,1',3',4'-hexa-O-acetylsucrose 
• 1315259-57-4 1'-O-(p-toluenesulfonyl)-6,6'-di-O-tert-butyldiphenylsilylsucrose 
• 81086-99-9 6,6'-(bis)-O-tert-butyldiphenylsilyl-2,3,4,1',3',4'-hexa-O-benzoylsucrose 

Relevant academic research and scientific papers

GEL FORMULATIONS FOR GUIDING RADIOTHERAPY

The present invention describes an X-ray contrast composition for local administration, wherein the X-ray contrast composition exhibits contrast properties and wherein at least 60% of an administrated amount of said X-ray contrast composition remains more

A synthesis of 6-deoxy-6-fluorosucrose suitable for PET applications

A new route to 6-deoxy-6-fluorosucrose has been developed. The process proceeds in 8 linear steps in 25% overall yield from sucrose. The steps incorporating fluorine and subsequent deprotection are quite rapid, making the procedure useful in the context o

Library of mild and economic protocols for the selective derivatization of sucrose under microwave irradiation

The chemistry of sucrose is very challenging due to its eight hydroxyl groups, three of which are primary, with very similar reactivities, thus control of the chemoselectivity is a central issue. In this work, the selective formation of monounsaturated es

Facile conversion of O-silyl protected sugars into their corresponding formates using POCl3·DMF complex

The direct O-formylation of two selectively protected sugar derivatives using the Vilsmeier-Haack (V-H) complex POCl3·DMF was studied. Primary O-TBDMS and O-TBDPS ethers of sucrose, the most common disaccharide, underwent regio and chemoselecti

SYNTHESIS AND REACTIONS OF tert-BUTYLDIPHENYLSILYL ETHERS OF SUCROSE

The reaction of sucrose with 1.1 mol. equiv. of tert-butyldiphenylsilyl (t-BDPS) chloride in pyridine in the presence of 4-dimethylaminopyridine gave the crystalline 6'-t-BDPS ether 1 in 49percent yield, without recourse to column chromatography.Compound 1 was transformed into the 4,6,1'-trichloride by using sulphuryl chloride.When the silylation reaction of sucrose was performed with 3 mol. equiv. of the reagent, chromatography gave the crystalline 6,6'-di-t-BDPS ether and the 6,1',6'-tri-t-BDPS ether 9 in yield of 78 and 18.7percent, respectively.Compound 9 was obtained as the major product on treatment of sucrose with 4.6 mol.equiv. of the silylating reagent.Removal of the silyl protecting-group in 6,6'-di-O-ter-butyldiphenylsilylsucrose hexabenzoate, using tetrabutylammonium fluoride, proceeded smoothly, but with 4->6 migration of the benzoate.