81086-94-4Relevant academic research and scientific papers
Porphyrins with directly meso -attached disaccharide moieties: Synthesis, self-assembly and cellular study
Malachowska, Magdalena,Sperduto, Claudio,Darmostuk, Mariia,Monti, Donato,Venanzi, Mariano,Mancini, Giovana,D'Acunto, Cosimo Walter,Králová, Jarmila,Ruml, Tomá?,Wimmer, Zdeněk,Dra?ar, Pavel B.
, p. 773 - 784 (2016/11/04)
A series of porphyrins with directly meso-attached "sucrose" moiety by the carbon C-6′ of its "fructose" end was synthesized, and their physico-chemical and aggregation properties studied by spectroscopic (fluorescence, circular dichroism, resonance light scattering) techniques. The effect of selected porphyrins on tumor cells was also evaluated.
Synthesis of 6′-deoxy-6′-fluorosucrose
Gaddam, Vikram,Harmata, Michael
, p. 38 - 41 (2013/05/09)
A facile synthesis of 6′-deoxy-6′-fluorosucrose has been developed. The title compound is available in six linear steps in 44% overall yield from commercially available sucrose. The synthesis involves rapid and convenient fluorination and deprotection con
SYNTHESIS AND REACTIONS OF tert-BUTYLDIPHENYLSILYL ETHERS OF SUCROSE
Karl, Horst,Lee, Cheang Kuan,Khan, Riaz
, p. 31 - 38 (2007/10/02)
The reaction of sucrose with 1.1 mol. equiv. of tert-butyldiphenylsilyl (t-BDPS) chloride in pyridine in the presence of 4-dimethylaminopyridine gave the crystalline 6'-t-BDPS ether 1 in 49percent yield, without recourse to column chromatography.Compound 1 was transformed into the 4,6,1'-trichloride by using sulphuryl chloride.When the silylation reaction of sucrose was performed with 3 mol. equiv. of the reagent, chromatography gave the crystalline 6,6'-di-t-BDPS ether and the 6,1',6'-tri-t-BDPS ether 9 in yield of 78 and 18.7percent, respectively.Compound 9 was obtained as the major product on treatment of sucrose with 4.6 mol.equiv. of the silylating reagent.Removal of the silyl protecting-group in 6,6'-di-O-ter-butyldiphenylsilylsucrose hexabenzoate, using tetrabutylammonium fluoride, proceeded smoothly, but with 4->6 migration of the benzoate.
