81090-31-5

Basic information

• Product Name: 2-bromo-N,4-dimethylaniline
• Synonyms: 2-bromo-N,4-dimethylaniline;(2-Bromo-4-methyl-phenyl)-methyl-amine
• CAS NO: 81090-31-5
• Molecular Formula: C₈H₁₀BrN
• Molecular Weight: 200.0757
• Mol File: 81090-31-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 119-120 °C(Press: 19 Torr)
• Appearance: /
• Density: 1.415±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.56±0.12(Predicted)
• CAS DataBase Reference: 2-bromo-N,4-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N,4-dimethylaniline(81090-31-5)
• EPA Substance Registry System: 2-bromo-N,4-dimethylaniline(81090-31-5)

Safety Data

• Hazardous Substances Data: 81090-31-5(Hazardous Substances Data)

Usage

General Description

2-bromo-N,4-dimethylaniline is a chemical compound classified as an aniline derivative. It is a substituted aromatic amine with a molecular formula of C8H10BrN. 2-bromo-N,4-dimethylaniline is characterized by a bromine atom attached to the second carbon of the aniline ring and two methyl groups attached to the fourth carbon. It is commonly used in the synthesis of various pharmaceuticals, agrochemicals, and dyes due to its reactivity and versatile chemical properties. Additionally, it is important to handle this compound with caution as it may be harmful if ingested, inhaled, or comes into contact with the skin or eyes.

Upstream product

• 353284-16-9 N-(2-bromo-4-methylphenyl)formamide 
• 583-68-6 2-bromo-p-toluidine 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 614-83-5 2-bromo-4-methylacetanilide 
• 87995-51-5 N-(2-bromo-4-methylphenyl)-N-methylacetamide 

Downstream Products

• 87995-66-2 2-Brom-N-(2,2-diphenylvinyl)-N,4-dimethylanilin 
• 87995-63-9 N¹-(2-Brom-4-methylphenyl)-N¹,4-dimethyl-N²-(4-methylphenyl)benzamidin 
• 1042743-85-0 3-[(2-bromo-4-methyl-N-methylanilino)methyl]-2H-chromen-2-one 
• 1174908-78-1 C₂₀H₂₁BrN₂O 
• 1174908-83-8 C₁₉H₁₉BrN₂O 
• 1205745-52-3 C₁₈H₁₈BrNO₂S 
• 1207518-08-8 N-methyl-4-methyl-2-(2-phenylethynyl)phenylamine 
• 24075-48-7 3,9-dimethyl-9H-carbazole 
• 1383675-36-2 1-benzyl-5,8-dimethyl-1H-[1,2,3]triazolo[4,5-c]quinolin-4(5H)-one 
• 1383675-56-6 1-benzyl-N-(2-bromo-4-methylphenyl)-N-methyl-1H-1,2,3-triazole-4-carboxamide 
• 1383675-20-4 N-(2-bromo-4-methylphenyl)-N-methylpropiolamide 

Relevant articles and documents

Preparation method for arylvinylsilane compound

The invention relates to the technical field of chemical synthesis and discloses a preparation method for an arylvinylsilane compound. The preparation method comprises the following steps: adding a raw material A, a raw material B, a catalytic precursor and an oxidant into a reaction medium, and conducting reacting at 25-80 DEG C for 1-24 h; and then conducting separating to obtain the arylvinylsilane compound, wherein the raw material A is an aromatic hydrocarbon compound containing a heteroatom orienting group, the raw material B is vinylsilane and the catalytic precursor is a palladium salt. According to the preparation method, the vinylsilane and the aromatic hydrocarbon compound containing the heteroatom orienting group are used as the raw materials, the palladium salt is used as thecatalytic precursor and the oxidants including silver acetate and the like are added; then the components are subjected to a one-step reaction in an organic solvent to synthesize a target product. Themethod provided by the invention has the advantages of relatively good adaptability to substrates containing substituent groups having different properties, high yield, good stereoselectivity, no need of ligands, no need of protection of inert gas and simplicity in operation.

Thermolysis and radiofluorination of diaryliodonium salts derived from anilines

Aniline-derived diaryliodonium salts were synthesized and functionalized in good to excellent yields by judicious utilization of electron-withdrawing protecting groups. This simple approach opens another route to radiolabeling amino arenes in relatively complex molecules, such as flutemetamol.

Palladium-catalyzed α-arylation of enones in the synthesis of 2-alkenylindoles and carbazoles

A new unified strategy has been developed for the synthesis of substituted 2-alkenylindoles and carbazoles. The strategy uses palladium-catalyzed α-arylation of TES-enol ethers of enones as the key step. The method is highly regioselective, provides good yields, and is expected to have wide application.