81090-82-6

Upstream product

• 63598-31-2 methyl 4,6-O-(R)-benzylidene-2-deoxy-α-D-erythrohexopyranosid-3-ulose 
• 174175-08-7 methyl 3-amino-4,6-O-benzylidene-2,3-dideoxy-α-D-ribo-hexopyranoside 
• 63598-32-3 4,6-O-benzylidene-2,3-dideoxy-α-D-erythro-hexopyranosid-3-ulose oxime 
• 127853-68-3 methyl 4,6-O-benzylidene-3-trifluoroacetamido-2,3-dideoxy-α-D-ribo-hexopyranoside 

Downstream Products

• 51996-45-3 2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose 
• 203498-57-1 Benzoic acid (2R,3S,4S,6S)-6-methoxy-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester 
• 203498-67-3 Benzoic acid (2R,3S,4S,6S)-6-hydroxy-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester 
• 203498-50-4 Benzoic acid (2S,3S,4S,6S)-2-iodomethyl-6-methoxy-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester 
• 81090-83-7 methyl 4-O-benzoyl-2,3,6-trideoxy-3-trifluoroacetamido-α-D-erythro-hex-5-enopyranoside 

Relevant academic research and scientific papers

A PRACTICABLE SYNTHESIS OF N-TRIFLUOROACETYL-L-DAUNOSAMINE FROM D-GlUCOSE

A synthesis of the N-trifluoroacetyl derivative of L-daunosamine, the glucidic component of adriamycin and daunomycin, two antibiotics with proved antineoplastic activity, is described starting from D-glucose, an inexpensive carbohydrate source.The synthetic sequence involves the stereoselective introduction of the C(3) amino group and the inversion at C(5), obtained by the stereospecific hydrogenation of a 5-methylenepyranose derivative, to flip from the D over the L series.