51996-45-3

Usage

Uses

Used in Pharmaceutical Research:
2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose is used as a research compound for its potential therapeutic properties, including its antibacterial and antiviral activities. It is valued for its capacity to contribute to the development of novel treatments and therapies.
Used in Organic Chemistry:
In the field of organic chemistry, 2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose is used as a building block for the synthesis of novel bioactive compounds. Its unique chemical structure allows for the creation of new molecules with potential applications in various chemical processes.
Used in Drug Discovery:
2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose is employed as a key component in drug discovery, where its unique properties can be leveraged to design and develop new pharmaceutical agents with improved efficacy and selectivity.
Used in Antibacterial Applications:
2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose is used as an antibacterial agent, targeting a range of bacterial infections. Its unique structure allows it to interact with bacterial cells in ways that traditional antibiotics may not, offering a potential new avenue for combating antibiotic-resistant bacteria.
Used in Antiviral Applications:
In antiviral research, 2,3,6-Trideoxy-3-trifluoroacetamido-L-lixo-hexopyranose is utilized for its potential to inhibit viral replication and infection. Its unique properties may provide a new approach to treating viral diseases, especially those that are resistant to existing antiviral medications.

Upstream product

• 56354-07-5 Methyl 2,3,6-trideoxy-3-trifluoroacetamido-α-L-threo-hexopyranoside-4-ulose 
• 91108-50-8 (-)-3-N-trifluoroacetyl-1,4-bis(O-trifluoroacetyl)-L-daunosamine 
• 73366-86-6 methyl 2,3,6-trideoxy-3-(trifluoroacetamido)-β-L-lyxo-hexopyranoside 
• 81090-83-7 methyl 4-O-benzoyl-2,3,6-trideoxy-3-trifluoroacetamido-α-D-erythro-hex-5-enopyranoside 
• 81090-82-6 methyl 4-O-benzoyl-6-bromo-2,3,6-trideoxy-3-trifluoroacetamido-α-D-ribo-hexopyranoside 
• 18977-93-0 L-Daunosamine hydrochloride 
• 68682-42-8 (2S,3S,6R)-3-hydroxy-6-methoxy-2-methyltetrahydro-4H-pyran-4-one 
• 56390-11-5 methyl 2,3,6-trideoxy-3-trifluoroacetamido-α-L-arabino-hexopyranoside 
• 72353-06-1 (2S,3R,6R)-3-Hydroxy-6-methoxy-2-methyl-tetrahydro-pyran-4-one oxime 
• 76390-10-8 C₁₁H₁₇NO₆ 
• 208942-28-3 2,2,2-Trifluoro-N-((2S,3R,4S)-3-hydroxy-6-methoxy-2-methyl-tetrahydro-pyran-4-yl)-acetamide 

Downstream Products

• 51996-41-9 Methyl-N-trifluoracetyldaunosaminid 
• 81275-35-6 1-O-acetyl-2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-L-lyxo-hexofuranoside 
• 81227-41-0 methyl 2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-β-L-lyxo-hexofuranoside 
• 81227-39-6 methyl 2,3,6-trideoxy-5-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-α-L-lyxo-hexofuranoside 
• 65222-75-5 (1S,2R,4S)-2-Ethyl-2,5,7-trihydroxy-4-((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 
• 65222-75-5 N-demethylaklavin 
• 78773-24-7 (1R,2R,4S)-2-Ethyl-2,5,7-trihydroxy-4-[(2R,4S,5S,6S)-6-methyl-4-[methyl-(2,2,2-trifluoro-acetyl)-amino]-5-(4-nitro-benzoyloxy)-tetrahydro-pyran-2-yloxy]-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 
• 78773-24-7 (1S,2S,4R)-2-Ethyl-2,5,7-trihydroxy-4-[(2R,4S,5S,6S)-6-methyl-4-[methyl-(2,2,2-trifluoro-acetyl)-amino]-5-(4-nitro-benzoyloxy)-tetrahydro-pyran-2-yloxy]-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 
• 78773-23-6 4-Nitro-benzoic acid (2S,3S,4S)-2-methyl-4-[methyl-(2,2,2-trifluoro-acetyl)-amino]-3,4-dihydro-2H-pyran-3-yl ester 
• 60504-57-6 aklavin 
• 57852-57-0 idarubicin hydrochloride 
• 91003-74-6 4-demethoxy-10,10-dimethyldaunomycin 
• 77398-05-1 (2S,3S,4S)-2-methyl-3-(4-nitrobenzoyloxy)-4-trifluoracetamido-3,4-dihydro-2H-pyran 
• 73352-88-2 4-O-acetyl-1,5-anhydro-2,6-dideoxy-3-trifluoroacetamido-L-lyxo-hex-1-enitol 

Relevant academic research and scientific papers

Addition of Hydrazoique Acid to Pseudoglycals Stereoselective Synthesis of L-Acosamine and L-Daunosamine

Methyl and benzyl glycosides and glycal of L-acosamine (3-amino-2,3,6 trideoxy-L-arabino-hexose) have been stereoselectively prepared via 1,4-addition of hydrazoic acid to L-erythro-hex-2-enopyranose as a key step.Inversion of the C-4 configuration of met

SYNTHESIS OF N-TRIFLUOROACETYL-L-ACOSAMINE, N-TRIFLUOROACETYL-L-DAUNOSAMINE, AND THEIR 1-THIO ANALOGS

A simple and efficient route to N-trifluoroacetyl-L-acosamine (13), N-trifluoroacetyl-L-daunosamine (12), and their 1-thio analogues (18 and 20) is described.Stereoselective reduction of oxime 5 with borane, followed by trifluoroacetylation resulted in the arabino methyl glycoside (8), which, on mild acid hydrolysis gave N-trifluoroacetyl-L-acosamine (13) in an overall yield of 33percent, based on L-rhamnal (1).Upon oxidation of the C-4 hydroxyl group and stereoselective reduction of the resulting ketone 11, compound 8 of L-arabino configuration was converted into N-trifluoroacetyl-L-daunosamine (12) in a one-flask sequence with an overall yield of 28percent calculated for 1.Benzyl 1-thio-N-trifluoroacetyl-α-L-acosaminide (18) was synthesized from enone 2 on Michael-type addition of phenylmethanethiol, followed by oximation, stereoselective reduction with borane and subsequent trifluoroacetylation. 4-O-Acetyl-1-S-acetyl-N-trifluoroacetyl-1-thio-β-L-daunosamine 20 was prepared from 12 via the corresponding glycosyl chloride derivative.