81093-21-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(Bromomethyl)-2,3-dimethylbenzene is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of a wide range of medicinal compounds, contributing to the advancement of drug discovery and therapeutic applications.
Used in Chemical Industry:
In the chemical industry, 1-(Bromomethyl)-2,3-dimethylbenzene is utilized as a key intermediate in the synthesis of dyes and pigments. Its bromomethyl group facilitates various chemical reactions, enabling the production of a diverse array of colorants used in different applications.
Used in Fragrance Industry:
1-(Bromomethyl)-2,3-dimethylbenzene is employed as a precursor in the fragrance industry. Its ability to undergo specific chemical transformations makes it suitable for the production of aromatic compounds that contribute to the creation of unique scents and perfumes.
Used in Research and Development:
This chemical compound is also used in research and development settings to explore new synthetic pathways and investigate its potential applications in various fields, including material science and nanotechnology. Its reactivity and structural features make it a valuable tool for scientific inquiry and innovation.

InChI:InChI=1/C9H11Br/c1-7-4-3-5-9(6-10)8(7)2/h3-5H,6H2,1-2H3

Upstream product

• 13651-14-4 (2,3-dimethylphenyl)methanol 
• 5779-93-1 2,3-dimethylbenzaldehyde 
• 603-79-2 2,3-dimethylbenzoic acid 

Downstream Products

• 81093-20-1 methyl 5-(2,3-dimethylphenyl)-3-oxopentanoate 
• 1053264-74-6 N-{(2R,3R,3aS,9aR)-2-[6-(2,3-Dimethyl-benzylamino)-purin-9-yl]-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl}-3-methoxy-benzamide 
• 849440-32-0 N-Boc-(S)-2',3'-dimethylphenylalanine 
• 96293-17-3 (S)-N-(2-benzoylphenyl)-1-benzylpyrrolidine-2-carboxamide 
• 1443541-14-7 4-(4-bromo-1-(2,3-dimethylbenzyl)-2-methyl-1H-benzo[d]imidazol-6-yl)morpholine 
• 1415664-03-7 C₂₄H₂₂N₆S 
• 1351646-48-4 4-[1-(2,3-dimethylbenzyl)-4-methoxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid 
• 1351646-18-8 4-[1-(2,3-dimethylbenzyl)-4-methoxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoate 
• 5779-93-1 2,3-dimethylbenzaldehyde 

Relevant academic research and scientific papers

Total syntheses of multicaulins via oxidative photocyclization of stilbenes

The Wittig reaction of 3-isopropyl-4-methoxybenzaldehyde and 2,3-dimethylbenzylphosphonium bromide afforded the corresponding stilbene mixture 16. Oxidative photocyclization of stilbene 16 with iodine facilitated the first total synthesis of 7-isopropyl-6

Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process

A convenient synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters via a domino process is described. The synthesis employs arylmethyl azides as the precursor which undergoes an acid-promoted rearrangement to give an N-aryl iminium ion. Following the addition with ethyl 3-ethoxyacrylate, intramolecular electrophilic aromatic substitution, elimination and subsequent oxidation, the quinoline products were obtained in moderate to excellent yields.

4. Synthese von Plectranthonen, diterpenoiden Phenanthren-1,4-chinonen

The following phenanthrene-1,4-diones have been synthesized by using the photocyclization of the corresponding highly substituted stilbenes as the key step: 3-hydroxy-5,7,8-trimethyl-2-(prop-2-enyl)phenanthrene-1,4-dione (1), (RS)-, (R)-, and (S)-2--1-methylethyl)acetate (2, 31, and 32, resp.), 3-hydroxy-7,8-dimethyl-2-(prop-2-enyl)phenanthrene-1,4-dione (3), 3-hydroxy-7,8,10-trimethyl-2-(prop-2-enyl)phenanthrene-1,4-dione (4), 5,7,8-trimethyl-2-(prop-2-enyl)phenanthrene-1,4-dione (17) and 3-hydroxy-2-methylphenanthrene-1,4-dione (42).The quinones 1 and 3 proved to be identical with recently isolated plectranthons A and C.Compounds 2, 31, and 32 exhibited the same UV/VIS, IR, 1H-NMR and mass spectra as natural plectranthon B, but had different melting points.This might be due either to crystal modifications or to diastereoisomerism caused by the helical structure of the phenanthrene-1,4-dione skeleton.The spectral data of synthetic 4 were not compatible with those of natural plectranthon D for which structure 4 had been proposed based mainly on 1H-NMR arguments concerning the chemical shifts of H-C(9) and H-C(10) in 1-3.Extensive 1H-NMR investigations have now revealed that the currently stated assignments of the H-C(9)/H-C(10) AB system have to be reversed for highly substituted phenanthrene-1,4-diones: in the model compounds 2-methylphenanthrene-1,4-dione (41) and 2, H-C(10) resonates at lower field as expected (peri-position), whereas in the highly substituted congeners 1, 2, 3, 31, and 32, H-C(9) is shifted paramagnetically, a fact which had lead to the erroneous assignment of structure 4 for natural plectranthon D.