81099-11-8

Basic information

• Product Name: (2R,4S)-3-(2-Chloro-acetyl)-2-(2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid methyl ester
• CAS NO: 81099-11-8
• Molecular Weight: 343.831
• Mol File: 81099-11-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4S)-3-(2-Chloro-acetyl)-2-(2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4S)-3-(2-Chloro-acetyl)-2-(2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid methyl ester(81099-11-8)
• EPA Substance Registry System: (2R,4S)-3-(2-Chloro-acetyl)-2-(2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid methyl ester(81099-11-8)

Safety Data

• Hazardous Substances Data: 81099-11-8(Hazardous Substances Data)

Upstream product

• 34297-27-3 D-penicillamine methyl ester hydrochloride 
• 90-02-8 salicylaldehyde 
• 79-04-9 chloroacetyl chloride 

Relevant articles and documents

Synthesis of Some 2,3-Dihydro-11bH-thiazolobenzoxazepin-5-(6H)one Derivatives. A New Heterocyclic Ring System

Condensation of (S)-penicillamine methyl or ethyl ester hydrochloride with salicylaldehyde and its C-5 derivatives, provided the diastereomeric thiazolidine derivatives 1 and 2.The resulting amino function was acylated to afford the amides 3 and 4.Cyclization of the latter led to the 2,3-dihydro-11bH-thiazolobenzoxazepin-5-(6H)ones 5 and 6.Conformational data for these heterocyclic compounds are discussed.